NFL Week 5 Sunday games have arrived, and we already have some injuries that will affect the slate.
Heading into Sunday, we have a number of key players already ruled out, and that list includes two key Eagles: running back Saquon Barkley and wide receiver DeVonta Smith, who will both miss Sunday morning's game in London. Other key players who will miss games on Sunday include: Bears running back Kyle Monangai, Patriots cornerback Christian Gonzalez and wide receiver Mack Hollins, Jets running back Breece Hall, and Ravens quarterback Lamar Jackson.
Justin Jefferson is active for the Vikings.
Keep it locked here for the latest injury news, full inactives for Sunday's games and injury updates as the games begin.
The 49ers are without one of their star receivers. 49ers WR Deebo Samuel is out for the remainder of the game with a hamstring injury.
The Chargers wide receiver situation continues to get worse. Wide receiver Tre' Harris (hamstring) is questionable to return.
49ers star wide receiver Deebo Samuel appeared to be in pain as he went down after a reception in the third quarter. He got attention from trainers as he stayed on the field for a bit after the apparent injury. The type of injury and extent of the injury are not yet known.
Lions linebacker Devin White is questionable to return with a forearm injury.
Browns running back Raheim Sanders is questionable to return with a hip injury.
Bengals offensive tackle Tytus Howard is questionable to return with a knee injury.
Giants S Tyler Nubin is questionable to return with a neck injury.
Patriots running back TreVeyon Henderson was downgraded to out with an ankle injury.
Packers cornerback Benjamin St-Juste is questionable to return with a hamstring injury.
Texans S Jalen Pitre is questionable to return with a shoulder injury.
Patriots cornerback Charles Woods is questionable to return with a shoulder injury.
Bengals linebacker Swayze Bozeman has a right arm injury and has been ruled out.
Giants right tackle Jermaine Eluemunor (calf) is questionable to return.
Jets tight end Kenyon Sadiq was ruled out after he was evaluated for a head injury.
Bears DB Tyrique Stevenson (Hamstring) is doubtful to return.
Steelers have ruled out WRs Roman Wilson (finger) and Ben Skowronek (calf).
Dolphins S Michael Taaffe has a chest injury and is questionable to return.
WR Irvin Charles (knee) and RB George Holani (ribs/knee) were both questionable heading into their game against the Niners.
As expected, DE Nick Bosa, who is dealing with a knee/calf injury, was ruled out ahead of the game. FB Kyle Juszczyk was also ruled out. DE Mykel Williams (knee), who started the season on the PUP list was questionable and is active.
DL Walter Nolen (calf) and LB Karson Sharar (hamstring) were the Cardinals' two questionable players this week.
DL Tyleik Williams was the Lions only questionable player and he is active.
Unlike their opponents this week, the Chargers have a lengthy injury report this week. WR Ladd McConkey (foot) was questionable and is active "but not expected to play meaningful snaps."
S Derwin James (hamstring) and WR Quentin Johnston (chest) were both ruled out ahead of the game.
Bears defensive lineman Dayo Odeyingbo is questionable to return with a quad injury.
Steelers WR Roman Wilson was downgraded to out with a groin injury.
Texans running back David Montgomery has been downgraded to out with a groin injury.
The Broncos only had two players with game designations. CB Riley Moss and CB Patrick Surtain were both ruled out.
Dolphins cornerback JuJu Brents is being evaluated for a concussion and is questionable to return.
Steelers wide receiver Roman Wilson went to the locker room with a wrist injury.
Patriots left tackle Will Campbell, who was questionable to return with a knee injury, is back on the sideline riding the bike. The knee injury is on the same knee that he injured last year, that caused him to miss time and then decline in performance when he returned.
Dolphins G Jonah Savaiinaea has an ankle injury and is questionable to return.
