Steelers vs. Colts odds, line, spread: 2020 NFL picks, Week 16 predictions from proven computer simulation
The SportsLine Projection Model has simulated Colts vs. Steelers 10,000 times

The Pittsburgh Steelers will take on the Indianapolis Colts at 1 p.m. ET on Sunday at Heinz Field. The Steelers are 11-3 overall and 6-1 at home, while Indianapolis is 10-4 overall and 5-2 on the road. The Colts can clinch a playoff berth with a win and losses by either the Ravens or Dolphins. The Steelers can clinch the AFC North title with a win or a Browns loss.
Indianapolis is favored by 1.5 points in the latest Steelers vs. Colts odds from William Hill Sportsbook, and the over-under is set at 44.5. Before entering any Colts vs. Steelers picks, you'll want to see the NFL predictions from the model at SportsLine.
The model, which simulates every NFL game 10,000 times, is up almost $7,900 for $100 players on top-rated NFL picks since its inception five-plus years ago. It is a sizzling 22-11 on top-rated NFL picks this season, returning over $800. The model also enters Week 16 on an incredible 118-76 run on top-rated NFL picks that dates back to the 2017 season.
The model ranked in the Top 10 on NFLPickWatch three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up.
Now, the model has set its sights on Steelers vs. Colts. You can head to SportsLine to see its picks. Here are several NFL betting lines for Colts vs. Steelers:
- Steelers vs. Colts spread: Steelers +1.5
- Steelers vs. Colts over-under: 44 points
- Steelers vs. Colts money line: Pittsburgh +110; Indianapolis -130
What you need to know about the Steelers
The Steelers are playoff bound, but lost a stunner at Cincinnati on Monday night, 27-17. It was Pittsburgh's third consecutive loss. The Bengals raced out to a 17-0 halftime lead and forced three Steelers turnovers. Cincinnati snapped an 11-game losing streak to Pittsburgh. The Steelers have not scored 20 points in their past four games. Ben Roethlisberger passed for 170 yards and TD vs. one INT last week. He has not thrown for 190 yards in his last two games.
Last week, T.J. Watt joined Hall of Famers Reggie White and Derrick Thomas as the only players to record at least 13 sacks in three of their first four seasons.
Stephon Tuitt had a sack in Week 15 and has a sack in three of his past four games. Diontae Johnson led the team with eight catches for 59 yards and a TD last week. He has eight-plus catches, 50-plus yards and a TD in two of his past three games. Mike Tomlin has a 6-1 record vs. the Colts. The Steelers have taken the last six games between the teams, including a 26-24 win on Nov. 3, 2019.
What you need to know about the Colts
Meanwhile, the Colts prevailed against the Houston Texans for their third consecutive win this past Sunday, 27-20. Zach Pascal had five catches for a season-high 79 yards and two TDs last week. He had five catches for 76 yards and a TD in the last meeting with the Steelers. T.Y. Hilton has 70-plus receiving yards in his past three games. He has a TD catch in three of his past four games. He is aiming for third game in row on the road with 85-plus. yards and a TD.
Jonathan Taylor rushed for 83 yards and a TD last week. He is shooting for his fifth game in a row with 95-plus scrimmage yards and his fourth in row with a TD. Taylor ranks second among rookies with 842 rushing yards and is tied for second with seven rushing TDs. Darius Leonard led the team with 12 tackles and had a forced fumble last week. He has 11-plus tackles in three of his past four games.
How to make Colts vs. Steelers picks
The model has simulated Steelers vs. Colts 10,000 times and the results are in. It is leaning under on the total, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You can only see the pick at SportsLine.
So who wins Colts vs. Steelers? And which side of the spread hits in well over 50 percent of simulations? Visit SportsLine now to see which side of the Colts vs. Steelers spread to jump on Sunday, all from the model that enters Week 16 of the NFL season on an incredible 118-76 roll.















