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USATSI

Joshua Dobbs will take the reins for the Tennessee Titans when they host the Jacksonville Jaguars with sky-high stakes on Saturday. The Titans will aim to stop a six-game losing streak against a Jaguars team that is on a four-game winning streak. Tennessee is 7-9 overall and 4-4 on the road, with Jacksonville entering at 8-8 overall and 4-3 at home. The winner will claim the AFC South title, with Jacksonville also winning the division with a tie.

Kickoff is at 8:15 p.m. ET in Jacksonville. Caesars Sportsbook lists Jacksonville as a 6.5-point home favorite, while the over/under, or total number of points Vegas thinks will be scored, is 40 in the latest Titans vs. Jaguars odds. Before locking in any Jaguars vs. Titans picks, make sure you check out the NFL predictions and betting advice from the SportsLine Projection Model. 

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 18 of the 2022 NFL season on an incredible 160-113 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 14-6 roll on top-rated NFL picks since Week 7 of this season.

The model ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has broken down Titans vs. Jaguars from every angle and locked in its NFL Week 18 picks and predictions. You can head to SportsLine now to see the model's picks. Here are several NFL odds and betting trends for Jaguars vs. Titans:

  • Titans vs. Jaguars spread: Jaguars -6.5
  • Titans vs. Jaguars over/under: 40 points
  • Titans vs. Jaguars money line: Jaguars -278, Titans +222
  • TENN: Titans are 5-2-1 against the spread in road games
  • JAX: Jaguars are 4-2 against the spread in home games
  • Titans vs. Jaguars picks: See picks at SportsLine

Why the Titans can cover 

The Titans are exceptionally well-coached under Mike Vrabel and, even with uncertainty at quarterback, Tennessee can lean on its defense and game-planning. The Titans are above-average in scoring defense, giving up only 21.2 points per game, and are elite against the run. The Titans give up only 80.5 rushing yards per game, No. 2 in the NFL, and Tennessee is in the top three in yards allowed per carry (3.4) and rushing touchdowns allowed (nine).

Tennessee is opportunistic with 14 interceptions, a top-eight mark, and the Titans excel on third down. Opponents convert only 33.6% of third down chances against Tennessee, and the Titans also have a special teams weapon in punter Ryan Stonehouse. He leads the NFL with 53.0 yards per punt, and that mark would set a new all-time league record for punting average in a season. See which side to back here.

Why the Jaguars can cover 

Jacksonville has the more explosive offense on paper in this matchup, as evidenced by a 36-point eruption in the first meeting against Tennessee. The Jaguars are also stout on defense as well, allowing three points in each of their last two games. Jacksonville has given up only 252 total yards per game in those contests and, for the season, the Jaguars are in the top 12 in scoring defense, allowing fewer than 21 points per game.

Jacksonville is a top-five team in creating turnovers (25), with a takeaway on 14.1% of defensive possessions. The Jaguars also yield only 4.2 yards per carry on the ground, and no team has a better fourth down efficiency (28.6%) on defense than Jacksonville. In addition, Tennessee's offense is weakened without quarterback Ryan Tannehill, and the Titans are No. 28 in the NFL in scoring offense and No. 30 in total offense. Tennessee is dead-last in the league in first downs, and the Titans haven't scored 28 points or more in any game this season. Tennessee is also the worst second-half scoring team in the NFL, generating 5.7 points per game, the fewest by any team since 2014. See which side to back here. 

How to make Jaguars vs. Titans picks

The model has simulated Saturday's Titans vs. Jaguars matchup 10,000 times. The model is leaning Under the total, predicting 37 combined points. The model also says one side of the spread cashes well over 50% of the time. You can only see the model's pick at SportsLine. 

So who wins Titans vs. Jaguars on Saturday? And which side of the spread cashes well over 50% of the time? Visit SportsLine right now to see which side of the Jaguars vs. Titans spread you should be all over Saturday, all from the model on a 160-113 roll on its top-rated NFL picks, and find out.