Chargers' Denzel Perryman: Available for wild-card round
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The NFL reinstated Perryman from a two-game suspension Monday, Tom Pelissero of NFL Network reports.
Perryman was handed a two-game suspension by the NFL in late December for "repeated violations of playing rules intended to protect the health and safety of players," per Daniel Popper of The Athletic. Perryman has served his suspension and will be available for the Chargers' wild-card game against the Patriots on Sunday. The veteran linebacker logged 47 tackles (30 solo) and three passes across 10 regular-season games.
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Marcus Maye: Cut by Bolts
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The Chargers waived Maye on Monday.
Maye was signed to the Chargers' active roster from the practice squad Saturday and served in a rotational role on defense during Sunday's 19-3 loss to the Broncos, when he logged five tackles (one solo) while playing 24 snaps (21 on defense, three on special teams). Maye could opt to remain with the Chargers as a member of the team's practice squad during the postseason.
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Chargers' Kendall Williamson: Leaves game with ankle injury
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Williamson (ankle) is questionable to return to Sunday's game against the Broncos.
Williamson has mostly served on special teams this season, but his absence depletes a Chargers secondary without the services of Derwin James (coach's decision) and Elijah Molden (hamstring) for Sunday's regular-season finale. The recently signed Marcus Maye should see more rotational snaps on defense for as long as Williamson is out of the game.
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Chargers' Bud Dupree: Leaves game with hamstring injury
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Dupree (hamstring) is questionable to return to Sunday's game against the Broncos.
Dupree was getting more snaps on defense in the absence of Tuli Tuipulotu (coach's decision), but the former is now being evaluated by medical staff for a hamstring injury. Odafe Oweh and Kyle Kennard are slated to see more work on defense if Dupree is unable to return.
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Chargers' Donte Jackson: Exits game with ankle injury
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Jackson (ankle) is questionable to return to Sunday's game against the Broncos.
Jackson had to be helped off the field after sustaining an ankle injury and couldn't put much weight on his leg, per Daniel Popper of The Athletic. Deane Leonard and Benjamin St-Juste are in line for more snaps in the secondary for as long as Jackson is out of the game.
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Chargers' Del'Shawn Phillips: Cleared to play Week 18
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Phillips (hamstring) is active for Sunday's game against the Broncos.
Phillips was a late addition to Saturday's injury report due to a hamstring injury, but he has been cleared to play in Sunday's regular-season finale. He's mostly served on special teams this season, but given that the Chargers are locked into a wild-card spot for the AFC playoffs, he may see more defensive snaps in Week 18 if Daiyan Henley operates on a snap count.
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Chargers' Tuli Tuipulotu: Healthy inactive for Week 18
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Tuipulotu (coach's decision) is inactive for Sunday's game against Denver.
Tuipulotu will join multiple key starters on the sidelines for Sunday's regular-season finale as the Chargers gear up for their postseason run. Bud Dupree, Odafe Oweh and Kyle Kennard are in line to see more defensive snaps in the absence of Tuipulotu, who will end the 2025 regular season with 49 tackles (35 solo), including a career-high 13.0 sacks, three pass defenses, two forced fumbles and one fumble recovery across 16 games.
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Chargers' RJ Mickens: Active for regular-season finale
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Mickens (shoulder) is active for Sunday's contest against the Broncos.
Mickens is good to go for Week 18 after missing the team's last two games while nursing a shoulder issue. With Derwin James (coach's decision) inactive for the regular-season finale, Mickens could draw the start at strong safety versus Denver.
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Chargers' Benjamin St-Juste: Good to go for Week 18
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St-Juste (shoulder) is active for Sunday's matchup with the Broncos.
St-Juste will make his return to action after missing the team's Week 17 loss to the Texans due to a shoulder injury. The 28-year-old will be back in his primary reserve role behind Donte Jackson and Cam Hart at cornerback against Denver.
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Chargers' Nikko Reed: Will miss most of postseason
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Reed (hamstring) was placed on injured reserve Saturday.
Reed has played sparingly this season, primarily on special teams. He'll now be out until at least the Super Bowl, should the Chargers advance that far in the postseason.
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Chargers' Del'Shawn Phillips: Pops up late on injury report
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Phillips (hamstring) is listed as questionable ahead of Sunday's game against the Broncos, Kris Rhim of ESPN.com reports.
Phillips has been healthy all season but must have picked up the injury late in the week during practice. He's primarily played on special teams this season, but the Chargers are projected to rest many of their starters. If Phillips, can suit up, he could be in line for a larger role as a result.
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Chargers' Marcus Maye: Signed to active roster
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The Chargers signed Maye from the practice squad to the active roster Saturday ahead of Sunday's game against the Broncos.
With Elijah Molden (hamstring) out and RJ Mickens (shoulder) questionable, Maye is set to be the primary backup at free safety for Sunday's game. If he suits up, Week 18 will be the defensive back's first game of the season, and he will likely fill a special-teams role if Mickens is inactive.
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Chargers' RJ Mickens: Still nursing injury
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Mickens (shoulder) was a limited participant in Wednesday's practice, Eric Smith of the Chargers' official site reports.
The rookie safety from Clemson has missed the Chargers' last two games due to a shoulder injury, but Wednesday's limited session suggests he could be nearing a return. Mickens likely needs to practice in full Thursday or Friday in order to avoid an injury designation for Sunday's regular-season finale against the Broncos.
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Chargers' Daiyan Henley: Double-digit stops vs. Houston
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Henley posted 10 tackles (two solo) during the Chargers' 20-16 loss to the Texans on Saturday.
Henley played every single defensive snap and tied a season high with 10 tackles during Saturday's loss. The third-year linebacker is now up to 102 combined tackles through 16 regular-season games, marking the second year in a row in which he cracked 100-plus tackles in a season.
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Chargers' Teair Tart: Ready for Saturday
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Tart (groin) is active for Saturday's matchup against the Texans.
The 28-year-old logged consecutive limited sessions to the end the Chargers' week of practice and is now ready to play in Saturday's contest. Tart is an important part of Los Angeles' defensive front, recording 28 total tackles, three passes defensed and one forced fumble over 15 appearances this season. He's expected to operate as the team's top nose tackle during the Week 17 matchup.
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Chargers' RJ Mickens: Sidelined for Week 17
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Mickens (shoulder) has been ruled out for Saturday's contest against the Texans.
Mickens will be forced to miss a second straight contest after suffering a shoulder injury in Week 15 versus the Chiefs. With Tony Jefferson and Derwin James back to full health, the absence of Mickens doesn't carry much of a defensive impact.
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Chargers' Bud Dupree: Ready to play Saturday
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Dupree (ankle) does not carry an injury designation for Saturday's game against the Texans.
Dupree began Week 17 with back-to-back limited practice sessions but was listed as a full participant on Thursday's estimated report. The veteran edge rusher will return from his one-game absence and suit up on the road versus Los Angeles on Saturday.
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Chargers' Teair Tart: Officially questionable for Week 17
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Tart (groin) is officially listed as questionable for Saturday's game against the Texans.
Tart missed practice Tuesday before upgrading to limited reps Wednesday, and he was also listed as a limited participant on Thursday's estimated report. Official word on Tart's status will arrive no later than 90 minutes prior to Saturday's 4:30 p.m. ET kickoff.
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Chargers' Benjamin St-Juste: Misses second straight practice
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St-Juste (shoulder) was a non-participant in practice both Tuesday and Wednesday.
St-Juste wasn't listed on an initial injury report shared by the Chargers on Tuesday, but he was added as DNP to one released later in the day. With another DNP designation Wednesday, it appears the veteran cornerback has a significant chance of missing Saturday's matchup against Houston. St-Juste will likely need to return to practice in some capacity Thursday to have a real chance of playing against the Texans.
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Chargers' Tuli Tuipulotu: Adds to sack total in Week 16 win
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Tuipulotu registered four tackles (two solo), including 1.0 sacks, and a fumble recovery during the Chargers' 34-17 win over the Cowboys on Sunday.
Tuipulotu got to Dak Prescott for a six-yard sack on the final play of the first half, and the former scooped up his first fumble of the season late in the fourth. Tuipulotu has accumulated 5.0 sacks across the four games since the Chargers' Week 12 bye, and his 13.0 sacks (across 15 regular-season games) are tied with Danielle Hunter for third most in the NFL behind Myles Garrett (22.0) and Brian Burns (15.0). Tuipulotu will look to add to his total against the Texans on Saturday, who are dealing with injuries to starting offensive tackles Aireontae Ersery (hand) and Trent Brown (knee).