Teams on differing streaks collide on 'Monday Night Football' as the 49ers visit the Colts. San Fran has won four straight, while Indy has dropped four in a row, as this contest will be very popular for wagering at many of the best DFS apps. Also, the likes of Christian McCaffrey, George Kittle, Jonathan Taylor and Philip Rivers will be sought after with NFL player props and by utilizing the latest Betr Picks promo code CBSSPORTS. You simply have to predict if a player will have 'More' or 'Less' a given statistical bar. This Betr Picks promotion gives new users $10 in bonus credits and a deposit match worth up to $200. Click here to get the latest Betr Picks promo code for new users:

How to claim the Betr Picks promotion on Monday, December 22

Here are the steps to follow in order to sign up and claim the Betr promo.

1. Click on the "Claim Bonus" link on the page or click here
2. Register for a Betr Picks account and enter the information requested
3. Make sure to enter the promo code "CBSSPORTS" when registering for an account
4. Make your first deposit of at least $10 and get a 50% deposit match worth up to $200 in Betr Bucks. To get the maximum deposit match bonus, you must deposit $400.
5. New users will also get an additional $10 in Betr Bucks upon completing registration. The Betr Bucks will be issued within one hour of registering, but please allow up to 24 hours for technical difficulties.

Betr will add up to $200 in Betr Bucks to your account after your first deposit, and you do not need to first play in any contests to secure the deposit match or registration bonus.

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Best Betr Picks for December 22

(Projections from the SportsLine model unless otherwise noted)

QB Philip Rivers, Colts, 157.5 passing yards - More

Rivers was contained in his return from retirement, but the Seattle defense he saw last week is miles ahead of the San Fran one he'll see on Monday. The Niners rank dead last in defensive sacks, which should allow the 44-year-old time to allow receivers to get open. Select it at Betr:

RB Christian McCaffrey, 49ers, 39.5 receiving yards - More

Indy owns the No. 6 run defense and has allowed the second-fewest rushing touchdowns. However, it is not nearly as strong in defending through the air, giving up the second-most receiving yards. Thus, San Francisco should utilize McCaffrey more in the passing game, and he's averaging 58.6 receiving yards per game in 2025. Click here to sign up for Betr Picks:

WR Jauan Jennings, 49ers, 4.5 receptions - Less

Ricky Pearsall is out for San Francisco, meaning Indianapolis can devote more attention to Jennings. The latter has been held to under 4.5 receptions in nine of 12 games this season. The model projects the wideout to have 3.8 catches on Monday Night Football. Combine picks for a parlay on Betr for a potential payout of 6x.

The SportsLine Projection model also offers picks for every NFL picks for every game on the slate, which you can use to help guide you in making NFL picks on Betr Picks.