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The No. 21 Ohio State Buckeyes will look to turn the tables on the No. 22 Wisconsin Badgers when they meet in a Big Ten Conference matchup in Columbus, Ohio, on Saturday. The Badgers (8-1, 1-0), who opened conference play with a 64-59 come-from-behind victory over Indiana on Wednesday, have won three of their last four games played at Ohio State. Wisconsin has started the season 8-1 for the second consecutive year and third time in the last four seasons. The Buckeyes (7-2, 1-0), who have won three straight, hold a 54-25 series edge in games played at home.

The game from Value City Arena is scheduled to tip off at noon ET. Wisconsin is averaging 69.9 points per game, while Ohio State averages 76.0. The Buckeyes are 4.5-point favorites in the latest Wisconsin vs. Ohio State odds from Caesars Sportsbook, while the over-under for total points scored is set at 135. Before making any Ohio State vs. Wisconsin picks, be sure to check out the college basketball predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $2,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Wisconsin vs. Ohio State and just locked in its picks and CBB predictions. You can visit SportsLine now to see the model's picks. Here are the college basketball odds and betting lines for Ohio State vs. Wisconsin:

  • Wisconsin vs. Ohio State spread: Ohio State -4.5 
  • Wisconsin vs. Ohio State over-under: 135 points 
  • Wisconsin vs. Ohio State money line: Ohio State -190, Wisconsin +160
  • WIS: The Badgers are 6-0 against the spread in their last six games overall 
  • OSU: The Buckeyes are 5-1 ATS in their last six Saturday games 

Why Ohio State can cover 

Sophomore forward Zed Key has come up big when the Buckeyes have needed him most. He scored 20 points in a 71-66 win over Duke on Nov. 30 in the Big Ten-ACC Challenge, and scored 13 points and grabbed nine rebounds in an 85-74 victory over Towson on Wednesday. He has reached double figures five times on the season. For the year, he is averaging 10.3 points, five rebounds and 0.9 blocks per game.

Senior forward Justin Ahrens is one of four Buckeyes to average at least nine points per game. He is averaging 9.1 points to go along with three rebounds and 1.3 assists. He is coming off a 16-point game against Towson where he was 5 of 10 from 3-point range. That was his fourth career game with five or more 3-pointers and he has done it twice this season. He is shooting 44 percent on the year from long range and leads the team with 24 made threes.

Why Wisconsin can cover

The Badgers have been led by sophomore guard Johnny Davis, who has scored in double figures in all eight games this season, including a season-high 30 in a 65-63 win over No. 12 Houston on Nov. 23 at the Maui Invitational. He is coming off a 23-point, nine-rebound performance in the victory over Indiana on Wednesday. For the season, Davis is averaging 20.5 points, third in the Big Ten. He also averages six rebounds, 2.3 assists and 1.4 steals per game.

Also powering the Badgers is fifth-year senior Brad Davison. He has reached double-digit scoring in five games, including three in which he scored 20 or more. He had a season-high 27 points in a 70-66 win at Georgia Tech in the Big Ten-ACC Challenge on Dec. 1. For the year, he is averaging 15 points, 4.4 rebounds and 1.9 assists, and is connecting on 83.8 percent of his free throws.

How to make Wisconsin vs. Ohio State picks

SportsLine's model is leaning over on the total, projecting 139 combined points. It has also generated an against-the-spread pick that cashes in well over 60 percent of simulations. You can only get the model's Ohio State vs. Wisconsin pick at SportsLine. 

So who wins Wisconsin vs. Ohio State? And which side of the spread hits in well over 60 percent of simulations? Visit SportsLine now to see which side of the Wisconsin vs. Ohio State spread to jump on, all from the advanced model that is up over $2,200 on its college basketball picks the last five years, and find out.