The Purdue Boilermakers have No. 1 seed talent with a No. 2 seed resume, which landed them in the East Region as the No. 7 overall team in the field of 68. They will face No. 15 seed Cal State Fullerton -- winners of the Big West Conference -- on Friday in the first round of the Big Dance.

So what side of Purdue-Cal State Fullerton do you need to be all over? Visit SportsLine now to get a strong pick from insider Mike Tierney, who's won three straight spread picks involving the Boilermakers.

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About No. 2 seed Purdue

There may not be a more complete team in the country than the Purdue Boilermakers when this experienced starting five is healthy. Four of Purdue's five starters are in their fourth season playing together; the fifth, sophomore Carsen Edwards, is this team's heart and soul. But a February three-game losing streak exposed Purdue's greatest weakness: When the 3-pointers aren't falling, they can be upset.

About No. 15 seed Cal State Fullerton

The Titans had a pretty unremarkable regular season, then turned it up for the Big West Tournament. They have the No. 1 free throw rate in the country, and if any opponent lets them live on the line, they're asking for trouble. Kyle Allman and Khalil Ahmad give them two potent scorers, but they don't do a great job taking care of the ball.

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The last two years, SportsLine's computer simulation correctly predicted nine out of 12 double-digit NCAA Tournament upsets in the first round with their computer algorithm. This year they have plenty of upsets again, like one region where you need to pick the 11, 12, AND 13 seeds, and another region with a 4-seed in the Final Four. Click here to see SportsLine's Optimized NCAA Tournament bracket.    

Live updates from Day Two of the NCAA Tournament

Embrace the madness!