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The 14th-ranked Houston Cougars (23-4) and SMU Mustangs (20-6) are set to square off in a must-see matchup on Sunday. Both teams enter Sunday's showdown full of confidence. The Mustangs have won four of their last five games, while the Cougars have won 15 of their last 17 overall. Houston has dominated this series in recent years, winning seven of the last 10 meetings against SMU.

Tip-off from the Fertitta Center is at 12:30 p.m. ET. The Cougars are favored by 10.5-points in the latest SMU vs. Houston odds from Caesars Sportsbook, while the over-under for total points is 137. Before locking in any Houston vs. SMU picks, be sure to see the college basketball predictions and betting advice from SportsLine's proven computer model. 

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,000 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on SMU vs. Houston, and just locked in its picks and CBB predictions. You can visit SportsLine now to see the picks. Here are the college basketball odds and betting lines for Houston vs. SMU.

  • SMU vs. Houston spread: Cougars -10.5
  • SMU vs. Houston over-under: 137 points
  • SMU vs. Houston money line: Mustangs +450, Cougars -650
  • HOU: The Cougars are 19-8 ATS in their last 27 games played on Sunday
  • SMU: The under is 6-1 in Mustang's last 7 road games

Why Houston can cover 

Senior guard Kyler Edwards is a solid scorer in the backcourt for the Cougars. Edwards is averaging 13.8 points, 5.9 rebounds, and 2.8 assists per game. The Texas native has scored at least 20 points four times over his last 11 outings. On Jan. 22 against ECU, Edwards recorded 25 points, eight rebounds, and seven assists. 

Senior center Josh Carlton provides the Cougars with some strength in the paint. Carlton is logging 11.7 points, 6.6 rebounds while shooting 62 percent from the field. The North Carolina native has recorded four double-doubles on the season. In the Feb. 20 double-overtime win against Wichita State, Carlton finished with 23 points and 11 rebounds. 

Why SMU can cover

Senior guard Kendric Davis has been the top scorer in the American Athletic Conference. He is currently first in the conference in scoring (19.3) to go along with 4.1 rebounds and 4.7 assists. Davis is also a solid shooter on the perimeter for the Mustangs. The Texas native is knocking down 37 percent of his shots from downtown. In the Feb. 9 matchup against Houston, Davis dropped 22 points, seven rebounds, and seven assists. 

Senior forward Marcus Weathers averages 12.6 points and 7.3 rebounds per game. He has tallied six double-doubles on the year. Over his past eight games, the Kansas native has scored at least 14 points in seven of those matchups. In the win over Tulsa, Weathers had 14 points, 13 rebounds, and three assists. 

How to make Houston vs. SMU picks

SportsLine's model is leaning over on the total, projecting 142 combined points. It also says one side of the spread hits almost 60 percent of the time. You can only get the model's pick at SportsLine. 

So who wins SMU vs. Houston? And which side of the spread hits almost 60 percent of the time? Visit SportsLine to see which side of the spread to jump on, all from the advanced model that is up almost $2,000 on its college basketball picks the last five-plus years, and find out.