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A Big East battle takes place on Wednesday when the St. John's Red Storm (15-13) hosts the Xavier Musketeers (17-11). Xavier has dominated this series over the years, winning 12 of the last 14 meetings. However, St. John's has won the last two head-to-head matchups, which includes an 86-73 victory on Feb. 16. 

Tip-off from Carnesecca Arena is at 6:30 p.m. ET. St. John's is favored by 1.5-points in the latest Xavier vs. St. John's odds from Caesars Sportsbook, while the over-under is 154.5. Before locking in any St. John's vs. Xavier picks, be sure to see the college basketball predictions and betting advice from SportsLine's proven computer model. 

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $1,700 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Xavier vs. St. John's, and just locked in its picks and CBB predictions. You can visit SportsLine now to see the picks. Here are the college basketball odds and betting lines for St. John's vs. Xavier.

  • Xavier vs. St. John's spread: Red Storm -1.5
  • Xavier vs. St. John's over-under: 154.5 points
  • Xavier vs. St. John's money line: Musketeers +105, Red Storm -125
  • XAV: The Under is 5-1 in Musketeers last 6 games following a double-digit loss at home
  • SJU: The Red Storm are 6-2 ATS in their last 8 games overall

Why St. John's can cover 

Sophomore guard Posh Alexander is a difference-maker in the backcourt for St. John's. He is currently second in the Big East in assists (5.2) and first in steals (2.4). He's also averaging 14.6 points per game. The New York native is a feisty defender who can finish strong at the rim. He's scored at least 15 points in 12 games. On Feb. 1 against Providence, Alexander recorded 29 points, five rebounds and 12 assists. 

Forward Aaron Wheeler is putting up 10.2 points and 4.4 rebounds. Wheeler is also one of the top 3-point shooters on the team. He is knocking down 41 percent of his attempts from downtown. Wheeler scored in double figures in eight of his last nine games. In his last outing, the Connecticut native finished with 20 points, seven rebounds, and three blocks. 

Why Xavier can cover

Junior forward Jack Nunge is logging a team-high 13 points along with 7.3 rebounds and 1.4 blocks. Nunge is versatile and can score from all over the floor. He is shooting 52 percent from the field and 33 percent from long rnage. The Indiana native has tallied more than 20 points in six outings this season. In the last contest against St. John's, Nunge finished with 22 points and seven rebounds. 

Sophomore guard Colby Jones averages 10.7 points, 7.7 rebounds, and 1.5 steals per game. Jones is aggressive on the glass, grabbing at least 10 rebounds in eight games. Five of those matchups resulted in a double-double. To wrap up the regular season against Seton Hall, Jones finished with a season-high 20 points, 10 rebounds, and four assists. 

How to make St. John's vs. Xavier picks

SportsLine's model is leaning under on the total, projecting 149 combined points. It also says one side of the spread hits almost 70 percent of the time. You can only get the model's pick at SportsLine. 

So who wins Xavier vs. St. John's? And which side of the spread hits almost 70 percent of the time? Visit SportsLine to see which side of the spread to jump on, all from the advanced model that is up over $1,700 on its college basketball picks the last five-plus years, and find out.