There are 15 games on the MLB schedule for Tuesday, and that means a ton of opportunities for bettors to cash in. Combining your picks into a parlay can bring an even bigger payout. Among the notable games Tuesday are an AL East matchup that could be a slug-fest and a pair of key early matchups in what should be a competitive NL East. The Blue Jays bring their stacked lineup to Yankee Stadium to face a New York lineup with plenty of pop of its own. They square off at 7:05 p.m. ET. The Mets face NL East rival Philadelphia at 6:45 p.m. ET after blowing a four run lead in a loss Monday night. And the Braves host the Nationals at 7:20 p.m. ET as they try to rebound from a humiliating 11-2 loss in Monday's series opener. There are plenty of other games of note as the teams start to build momentum after the delayed start to the season.

The Yankees, Braves and Phillies are all home favorites in the latest MLB odds from Caesars Sportsbook. New York is priced at -130 (risk $130 to win $100) on the moneyline in the latest MLB odds, while Philadelphia is listed at -150 and Atlanta is -160. Before locking in any MLB picks or parlays, be sure to check out the MLB predictions and betting advice from SportsLine's proven computer model.

This model, which simulates every game 10,000 times, enters Week 2 of the 2022 season on a 216-181 roll on top-rated MLB money-line picks that dates back to last season, returning over $900 for $100 players. Anyone following it has seen huge returns.

Now, the model has locked in four confident MLB best bets for Tuesday, and they all involve games starting at 7:40 p.m. ET or later, so there is plenty of time to get your MLB picks in. If you successfully parlay the picks, you'd be looking at a payout of well over 11-1. You can only see the model's MLB picks for Tuesday at SportsLine. 

Top MLB picks today

After simulating each of Tuesday's games 10,000 times, one pick it really likes is Houston (-160) to beat Arizona (9:40 p.m. ET). The Astros' lineup is superior, and they show no signs of slowing down after losing in the World Series last season. They won three of four in the season-opening series with the Angels, scoring 20 runs in the process. Arizona scored 11 runs in its four against the Padres, losing three in a row after a walk-off win in the opener.

The Astros hit eight home runs in the opening series, and 32-year-old Arizona starter Madison Bumgarner has struggled in his first two seasons with the team. He had a 4.67 ERA last season and was at 6.48 in nine starts in 2020. Houston's pitchers lead the majors in ERA at 1.80 and have a WHIP of 1.06. It is set to start 25-year-old right-hander Luis Garcia, who was 11-8 with a 3.48 ERA last season. He will face a Diamondbacks lineup that hit .129 in the first four games.

How to make MLB parlays for Tuesday

The model has locked in three other best bets for Tuesday, including a play on a road underdog with excellent value, to combine in a parlay paying more than 11-1. You can only see the model's MLB parlay picks and best bets for Tuesday at SportsLine. 

What MLB picks should you target for a payout of more than 11-1? And what road underdog can help you cash in big? Visit SportsLine now to see the MLB best bets for Tuesday from the model on a 216-181 roll dating to last season on top-rated MLB money-line picks, and find out.