Twins vs. Tigers odds, line: 2021 MLB picks, predictions for July 16 from proven computer model
SportsLine's advanced computer model simulated Tigers vs. Twins 10,000 times

American League Central rivals look to turn around their fortunes after a disappointing first half to the season when the Minnesota Twins face the Detroit Tigers in the first game of a doubleheader on Friday. Both games are scheduled to go seven innings. The Twins (39-50), who were expected to challenge for the division title, are fourth in the division, 15 games behind first-place Chicago. The Tigers (40-51), who are percentage points ahead of Minnesota for third place, have performed better at home and are 21-22 there in 2021.
First pitch is set for 2:10 p.m. ET from Comerica Park in Detroit. The Tigers lead the all-time series 1,138-1,063, including a 604-500 edge in home games. The Twins are a -115 favorite on the money line in the latest Twins vs. Tigers odds from William Hill Sportsbook, while the over-under for total runs scored is seven. Before making any Tigers vs. Twins picks, check out the latest MLB predictions from the SportsLine Projection Model.
This model, which simulates every pitch of every game 10,000 times, had a banner 2019 season, the league's last full schedule, returning more than $1,400 on its top-rated money-line and run-line MLB picks. In the first half of the 2021 season, it went 120-96 on top-rated MLB money-line picks, returning almost $400. Anyone following it has seen huge returns.
Now, the model has dialed in on Twins vs. Tigers picks and predictions. You can visit SportsLine now to see the picks. Here are the MLB odds and trends for Tigers vs. Twins:
- Twins vs. Tigers money line: Minnesota -115, Detroit +105
- Twins vs. Tigers run line: Minnesota -1.5 (+140)
- Twins vs. Tigers over-under: 7 runs
- MIN: The Twins have won 13 of the past 20 games in the series at Detroit
- DET: Tigers batters are 13th in MLB with 704 hits this season
Why you should back the Tigers
Second baseman Jonathan Schoop has been red hot. He has a five-game hitting streak, including a pair of multiple-hit performances in that stretch. Last weekend at Minnesota, Schoop was 6-for-17 (.353) with a double and two RBIs. In 50 career games against the Twins, Schoop is hitting .235 with seven doubles, two triples, five homers and 17 RBIs. He finished the season's unofficial first half hitting .277 with 16 homers, 52 RBIs and 45 runs scored.
Outfielder Robbie Grossman has also been solid at the plate of late. He had a five-game hitting streak snapped on Sunday. Although he is hitting just .226, he has an on-base percentage of .354 with 12 homers, 42 RBIs and 44 runs scored. In eight games against the Twins this season, he is hitting .241 with two doubles, two homers and five RBIs. He has dominated Minnesota pitching in the past. In 26 career games against the Twins, he is hitting .330 with six doubles, two homers and eight RBIs.
Why you should back the Twins
Minnesota is coming off a four-game sweep of Detroit last weekend at home, averaging 7.5 runs per game in doing so. Second baseman Jorge Polanco had a monster game in Sunday's win, going 3-for-6 with a homer and five RBIs. In his last five games, Polanco is 7-for-19 (.368) with two homers and nine RBIs. He has feasted on Tigers pitching all season. In nine games against Detroit, he is hitting .351 with three doubles, three homers and 14 RBIs with a .676 slugging percentage.
Also powering the Twins offense is outfielder Nelson Cruz, who is hitting .304 this season with 18 homers, 46 RBIs and 41 runs scored. In Saturday's 9-4 win over Detroit, Cruz was 3-for-3 with a walk, stolen base and run scored. In nine games against the Tigers this season, Cruz is batting .351 with a double, three homers, five walks and seven RBIs. He has a .622 slugging percentage and 1.040 OPS vs. Detroit.
How to make Tigers vs. Twins picks
SportsLine's model is leaning over on the run total, as the simulations project the teams will combine for 8.9 runs, and it also says one side of the money line has the value. You can only get the model's MLB picks at SportsLine.
So who wins Twins vs. Tigers? And which side of the money line has all the value? Visit SportsLine now to see which side of the Tigers vs. Twins money line to jump on Friday, all from the advanced model that has returned nearly $400 on MLB picks in 2021, and find out.















