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USA TODAY Sports

The Timberwolves vs. Cavaliers game features the top two scoring defenses, albeit the game will be devoid of Karl-Anthony Towns (knee), Donovan Mitchell (knee) and Evan Mobley (ankle). With players of that magnitude out, NBA prop bettors will focus on the likes of Anthony Edwards, Rudy Gobert, Darius Garland and Jarrett Allen. Gobert is particularly of interest for player props, as the absences of Towns and Mobley could make him a beast on the boards. He's averaged 16 rebounds in his three games without Towns this season, and his NBA props total is 14.5 rebounds for tonight's contest.

Meanwhile, Edwards' blocks total in his NBA prop bets is 0.5, with plus-money prop odds (+159) if he goes Over. The emerging superstar had a game-saving, highlight-worthy block against Indiana on Thursday, and he has six blocks over his last seven games. Just a single swat is all you need from Edwards to cash in on this plus-money payout, so can you count on him as part of a winning NBA props parlay? Before making any NBA prop picks on sites like PrizePicks for Friday, be sure to check out the NBA predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past five-plus seasons. The model enters Week 20 of the 2023-24 NBA season on a sizzling 64-40 roll on all top-rated NBA picks this season, returning more than $2,200. Anyone following it has seen huge returns.

For Friday's NBA schedule, the model has locked in its NBA best bets. You can only see the model's NBA prop picks at SportsLine. 

Top NBA prop bet for Friday

After simulating every game on Friday's NBA schedule 10,000 times, the model is picking Under 13.5 rebounds for Lakers center Anthony Davis at -147 odds. Davis' season average comes under the bar as he's putting up 12.3 rebounds per night, and he's snagged 12 boards or fewer in each of his last three games. Also, some players have a knack for performing better or worse on certain nights of the week, and Davis is averaging just 10.3 rebounds across six Friday games, which are his fewest of any day of the week.

The Lakers host the Bucks tonight at 10 p.m. ET, and Milwaukee ranks second in the NBA in defensive rebounds per game, which obviously would limit second-chance opportunities for all Lakers. Additionally, the length of Giannis Antetokounmpo and Brook Lopez has limited Davis' production on the glass as he's gone Under 13.5 rebounds in 11 of his last 12 games versus the Bucks. He's averaging 10.5 rebounds over this stretch, while the model calls for Davis to snag 10.6 boards on average tonight. You can see which other NBA picks to back here.

All NBA prop bets for Friday's NBA schedule

7 p.m. ET: Pelicans vs. 76ers
See 76ers vs. Pelicans props here

7 p.m. ET: Hornets vs. Wizards
See Wizards vs. Hornets props here

7:30 p.m. ET: Timberwolves vs. Cavaliers
See Cavaliers vs. Timberwolves props here

7:30 p.m. ET: Magic vs. Knicks
See Knicks vs. Magic props here

8 p.m. ET: Hawks vs. Grizzlies
See Grizzlies vs. Hawks props here

8 p.m. ET: Heat vs. Thunder
See Thunder vs. Heat props here

10 p.m. ET: Bucks vs. Lakers
See Lakers vs. Bucks props here

10 p.m. ET: Rockets vs. Trail Blazers
See Trail Blazers vs. Rockets props here

How to make NBA prop picks for Friday

The model has simulated every NBA game 10,000 times and has some surprising projections for Friday's schedule. You can only see the model's NBA best bets and SGP picks at SportsLine. 

Which NBA prop picks should you target on Friday? Visit SportsLine now to see the NBA best bets from an advanced model that is on a 64-40 run on top-rated NBA picks, and find out.