puka-nacua-los-angeles-rams
Imagn Images

The NFL Week 18 schedule features two games on Saturday and 14 on Sunday, including a 'Sunday Night Football' matchup between the Baltimore Ravens and Pittsburgh Steelers. The AFC North title and a playoff spot will be on the line when Derrick Henry and the Ravens battle Aaron Rodgers and the Pittsburgh Steelers. The NFC South championship will also be on the line when the Carolina Panthers take on the Tampa Bay Buccaneers on Saturday afternoon. The Ravens are favored by 3.5 points at DraftKings Sportsbook, while the Seahawks are 2.5-point favorites.

Sunday's largest spreads include Titans vs. Jaguars (-13.5), Colts vs. Texans (-10.5) and Dolphins vs. Patriots (-11.5). Besides the Seahawks vs. 49ers, the smallest spreads in Week 18 include Saints vs. Falcons (-3.5), Lions vs. Bears (-3) on Sunday and Panthers vs. Buccaneers (-3) on Saturday. Seattle, San Francisco and Denver all face scenarios where if they win, then they claim their respective conference's No. 1 overall seed. 

Before making any Week 18 NFL picks or NFL score predictions on those games or others, you need to see the NFL against the spread, over/under and money line predictions powered by the self-learning SportsLine AI.

Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team's historical data and then quantitatively evaluating the strength of the opponent's defense by assigning a numeric value out of 100 called a matchup score. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. SportsLine's AI PickBot has hit more than 2,000 4.5- and 5-star prop picks since the start of the 2023 season. 

For Week 18 NFL betting, SportsLine AI has evaluated the NFL odds and provided NFL betting picks for all 16 games. You can only see the AI predictions for the Week 18 NFL schedule here.

Top Week 18 NFL AI picks

After analyzing every game in Week 18, the AI says the Rams (-8.5, 46.5), who have already clinched a postseason berth, cover comfortably against the Cardinals. 

The Cardinals have gone over in five of their last eight games, while the over has hit in three of the last four head-to-head meetings. Bet the Over 47.5 in the latest DraftKings promo code, which offers $200 in bonus bets if your first bet wins:

Los Angeles has won seven of the last 10 meetings with Arizona and is expected to win comfortably once again. A win would be their third in a row over the Cardinals. Los Angeles earned a 45-17 win in the Dec. 7 meeting at Arizona. SportsLine AI rates the Steelers as a B spread pick and also predicts a 31-20 win on average. See its other Week 18 football predictions and football picks at SportsLine, and bet the Rams at DraftKings here:

How to make Week 18 NFL picks

In addition, the AI PickBot has generated more than two dozen highly-coveted A picks for Week 18. You need to see the AI's NFL picks before making any Week 18 NFL bets of your own. You can only see them at SportsLine.

Who wins and covers each Week 18 NFL game, and which A+ picks should you target now? Visit SportsLine now to see the top NFL picks against the spread, over-under and on the money line, all from the SportsLine AI that has nailed more than 2,000 highly-rated picks since the start of the 2023 season.