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The Colorado Buffaloes and the No. 2 Arizona Wildcats are set to square off in a 2022 Pac-12 Tournament matchup at 9 p.m. ET on Friday at T-Mobile Arena. The Buffaloes are 21-10 while Arizona is 29-3. These teams split their regular-season series, with the road team winning on both occasions. 

The Wildcats are favored by 9.5 points in the latest Arizona vs. Colorado odds from Caesars Sportsbook, while the over-under is set at 148. Before entering any Colorado vs. Arizona picks, you'll want to see the college basketball predictions from the model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $1,600 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Arizona vs. Colorado. You can head to SportsLine to see its picks. Here are several college basketball odds for Colorado vs. Arizona:

  • Arizona vs. Colorado spread: Arizona -9.5
  • Arizona vs. Colorado over-under: 148 points

What you need to know about Arizona

Arizona has been one of the top teams in college basketball this season. The Wildcats have only lost three games, with all three of those setbacks coming on the road. They finished the regular season on a three-game winning streak and added an 84-80 win over Stanford on Thursday to open their tournament run. 

Freshman guard Bennedict Mathurin leads Arizona with 17.3 points and 5.7 rebounds per game, while freshman forward Azuolas Tubelis is adding 14.5 points. Freshman guard Kerr Kriisa, who averages 10.1 points, is not expected to play on Friday after injuring his ankle on Thursday. The Wildcats have won 13 of their last 14 conference games. 

What you need to know about Colorado

Colorado won seven of its last eight games down the stretch of the regular season, including an upset win over Arizona on Feb. 26. The Buffaloes were able to build on that momentum with an 84-71 win at Utah last Saturday. They got off to a strong start in the Pac-12 Tournament on Thursday, recording an 80-69 win over fifth-seeded Oregon. 

Sophomore forward Jabari Walker leads Colorado with 14.8 points and 9.6 rebounds per game. Senior forward Evan Battey is scoring 12.4 points, while sophomore guard Keeshawn Barthelemy is adding 10.9 points. The Buffaloes have covered the spread in six of their last seven games. 

How to make Colorado vs. Arizona picks

The model is leaning under on the total, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Colorado vs. Arizona? And which side covers well over 50 percent of the time? Visit SportsLine now to find out, all from the model that has crushed its college basketball picks.