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USATSI

No. 8 seed San Diego State will square off against No. 9 seed Creighton in a Midwest Region showdown in the NCAA Tournament on Thursday evening. The Aztecs have gone 23-8 this season, losing to Boise State by one point in the Mountain West Tournament title game. Creighton is coming off a loss to Villanova in the Big East Championship, putting its record at 22-11 entering the Big Dance.

Tipoff is set for 7:27 p.m. ET at Dickies Arena. Caesars Sportsbook lists the Aztecs as two-point favorites in the latest San Diego State vs. Creighton odds. The total for points scored is set at 121. Before entering any Creighton vs. San Diego State picks, be sure to check out the college basketball predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $1,500 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on San Diego State vs. Creighton and revealed its coveted picks and predictions for the NCAA Tournament 2022. You can head to SportsLine to see all of the model's college basketball picks. Here are several college basketball odds and trends for San Diego State vs. Creighton:

  • San Diego State vs. Creighton spread: San Diego State -2
  • San Diego State vs. Creighton over-under: 121 points
  • San Diego State vs. Creighton money line: San Diego State -140, Creighton +120
  • Creighton: The Bluejays are 4-7 against the spread in non-conference games
  • San Diego State: The Aztecs are 5-4 against the spread in non-conference games

What you need to know about Creighton

Creighton had a slow finish to the regular season, losing two of its final three games. The Bluejays bounced back with wins over Marquette and Providence in the Big East Tournament before eventually losing to Villanova in the title game. They rely on a defense that ranks ninth nationally in 2-point field goal percentage. 

Senior forward Ryan Hawkins leads a balanced Creighton offense with 13.9 points and 7.8 rebounds per game. Center Ryan Kalkbrenner, guard Alex O'Connell and guard Ryan Nembhard are all averaging double figures as well, but Nembhard is out for the season with a wrist injury. The Bluejays have covered the spread in six of their last seven games as underdogs. 

What you need to know about San Diego State 

San Diego State has been one of the best defensive teams in college basketball this season, ranking second nationally in KenPom's adjusted efficiency ratings. Defense wins games in the NCAA Tournament, as the pace is generally slower than the regular season. The Aztecs rank inside the top 30 in defensive field goal percentage, block percentage and turnover rate.

They are facing an inexperienced Creighton squad that has dealt with turnover issues throughout the season. San Diego State is one of the most experienced teams in the country, which gives the Aztecs an edge on Thursday. They have covered the spread in seven of their last 10 games this season. 

How to make Creighton vs. San Diego State picks

SportsLine's model is leaning over on the point total, projecting the teams to combine for 130 points. The model also says one side of the spread has all the value. You can only see the model's pick at SportsLine.

So who wins San Diego State vs. Creighton? And which side of the spread has all the value? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that has crushed its college basketball picks, and find out.