DePaul vs. Butler prediction, odds, line: 2022 college basketball picks, Feb. 15 best bets from proven model
SportsLine's model revealed its CBB picks and predictions for Butler vs. DePaul on Feb. 15

The DePaul Blue Demons (12-11) and the Butler Bulldogs (12-13) will face off in a Big East clash at 9 p.m. ET on Tuesday, Feb. 15 at Wintrust Arena. Butler snapped a three-game losing streak with its 85-79 win over Marquette on Saturday, while DePaul fell to Providence 76-73 in overtime in its last outing.
DePaul is favored by 3.5 points in the latest DePaul vs. Butler odds from Caesars Sportsbook, and the over-under is set at 129. Before making any Butler vs. DePaul picks, you need to see the college basketball predictions and betting advice from the red-hot computer simulation model at SportsLine.
The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,000 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.
Now, the model has set its sights on DePaul vs. Butler, and just revealed its picks and CBB predictions. You can head to SportsLine now to see the model's picks. Here are several college basketball odds and betting lines for DePaul vs. Butler:
- DePaul vs. Butler spread: DePaul -3.5
- DePaul vs. Butler over-under: 129 points
- DePaul vs. Butler moneyline: Butler +145, DePaul -170
What you need to know about DePaul
The Blue Demons were close but no cigar this past Saturday as they fell 76-73 to the Providence Friars. DePaul got double-digit scores from five players: forward David Jones (19), guard Jalen Terry (15), center Nick Ongenda (11), guard Courvoisier McCauley (10), and forward Brandon Johnson (10).
DePaul has struggled mightily since late December, going 3-10 in its last 13 games. Jones has been a bright spot for the Blue Demons, however, with the sophomore forward averaging 14.7 points, 7.7 rebounds, and 2.3 assists per game. DePaul is 15-8 against the spread in 2021-22.
What you need to know about Butler
Meanwhile, the Marquette Golden Eagles typically have all the answers at home, but this past Saturday Butler proved too difficult a challenge. Butler secured an 85-79 win over the Golden Eagles. The Bulldogs can attribute much of their success to forward Bryce Golden, who had 22 points, and forward Bryce Nze, who had 12 points in addition to nine rebounds.
Butler won its previous meeting against DePaul 63-59 on Dec. 29. The Bulldogs, who have lost seven of their last 10 games, desperately need to get back on track before the Big East Tournament opens in March. Chuck Harris, Bo Hodges, and Jayden Taylor combine to give the Bulldogs on the more dynamic backcourts in the conference. Butler is 10-15 against the spread in 2021-22.
How to make DePaul vs. Butler picks
The model has simulated DePaul vs. Butler 10,000 times and the results are in. We can tell you that the model is leaning Over on the point total, and it's also generated a point-spread pick that is hitting in well over 60 percent of simulations. You can only see the model's Butler vs. DePaul pick at SportsLine.
So who wins Butler vs. DePaul? And which side of the spread hits in well over 60 percent of simulations? Visit SportsLine now to see which side of the DePaul vs. Butler spread to jump on, all from the advanced model that is up more than $2,000 on its college basketball picks the last five years, and find out.















