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Plenty of star power will be on display Monday when DeMar DeRozan, Zach LaVine and the Chicago Bulls travel to take on Joel Embiid, James Harden and the Philadelphia 76ers. This could be a preview of an NBA Eastern Conference playoff series. The Sixers currently occupy the No. 2 seed in the East with a 39-24 record. Chicago (39-25) is close behind at No. 4. Chicago center Nikola Vucevic (hamstring) is questionable for this one.

Tipoff at the Wells Fargo Center is set for 7 p.m. ET. Caesars Sportsbook lists Philadelphia as the seven-point favorite in the latest 76ers vs. Bulls odds. The over-under for total points is set at 232.5. Before locking in any 76ers vs. Bulls picks, be sure to see the NBA predictions and betting advice from SportsLine's proven computer model. 

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past three-plus seasons. The model enters Week 20 of the 2021-22 NBA season on a stunning 74-47 roll on all top-rated NBA picks, returning almost $2,100. Anyone following it has seen huge returns.

Now, the model has set its sights on Sixers vs. Bulls, and just locked in its picks and NBA predictions. You can head to SportsLine now to see the model's picks. Here are several NBA odds and betting lines for Bulls vs. Sixers:

  • Bulls vs. 76ers spread: 76ers -7
  • Bulls vs. 76ers over-under: 232.5 points
  • Bulls vs. 76ers money line: 76ers -300, Bulls +240
  • CHI: The Bulls are 23-17 against the spread in conference games
  • PHL: The 76ers are 18-20 against the spread in conference games

Why the Bulls can cover

Chicago has strong defensive metrics in key areas, including top-10 marks in defensive rebound rate, second-chance points allowed, and 3-pointers allowed per game. However, the Bulls are buoyed by a dynamic and prolific offense. Chicago ranks in the top five of the NBA in offensive efficiency, scoring 113.2 points per 100 possessions. The Bulls lead the league in field-goal percentage at 48.4 percent, and Chicago is in the top three of the NBA in 3-point percentage (37.6 percent) and free-throw percentage (81.3 percent). 

Ball security is a strength for the Bulls, turning the ball over on only 13.0 percent of possessions, and Chicago is above-average in producing 24.3 assists per game. The Bulls round out the offense with a top-10 mark in fast-break points (12.9 per game), and Philadelphia is last in the NBA in offensive rebound rate at only 23.9 percent.

Why the 76ers can cover

Harden, who is expected to be back in the lineup after resting over the weekend, has given Philadelphia a new dimension on offense. In his four appearances since being traded from Brooklyn, he's scored at least 26 points each time out. He's shooting a blistering 60.9 percent from the field over his last two games.

He's also getting teammates involved, averaging 12 assists per contest since the trade. The Sixers have won all four games Harden has appeared in and went 3-1 against the spread during that span. Philadelphia also has a 3-0 ATS mark against Chicago this season. 

How to make Bulls vs. 76ers picks

SportsLine's model is leaning under on the total, predicting 228 combined points. The model also says one side of the spread hits well over 50 percent of simulations. You can only see the model's pick at SportsLine.

So who wins 76ers vs. Bulls? And which side of the spread hits well over 50 percent of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has crushed its NBA picks, and find out.