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The San Francisco 49ers have dealt with a lot of injuries this season, and they received another major blow after superstar Nick Bosa tore his ACL and is out for the remainder of the season. With San Francisco now without its top pass rusher, how does that impact the team's Super Bowl chances after a 3-0 start?

The top sportsbooks have already responded to the injury in futures markets, with FanDuel moving the 49ers from -105 to +110 to win the NFC West. San Francisco is now +2000 to win it all after Bosa's injury, up from +1700 with him healthy. 

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Even though the 49ers are 3-0, these injuries are ultimately expected to catch up with them when the games really start to matter. CBS Sports' Stephen Oh projects the 49ers at 10.2 wins without Bosa, down from 10.7 wins with him in the lineup. Oh notes that is a substantial drop for a non-quarterback injury. The 49ers now have a 40.8% chance to win the division without Bosa, down 6% from the original projection of 46.8% with him in the lineup. The team still has a 76.4% chance to make the playoffs thanks to the 3-0 start and a relatively soft schedule, but that number is down from the 81.6% chance it had with Bosa healthy.

49ers projectionsWin totalDivisionMake playoffsNFC champWin Super Bowl
With Bosa10.762.90%46.80%81.60%2.10%
Without Bosa10.260%40.80%76.40%1.20%
Change-0.5-2.90%-6%-5.20%-0.90%

The 49ers take a major hit when it comes to NFC title and Super Bowl odds. Per Oh's projections, San Francisco had a 6.2% chance to win the NFC and 2.1% chance to win the Super Bowl with Bosa healthy, but those numbers are down to 3.6% and 1.2% respectively. 

San Francisco hosts the 2-1 Jacksonville Jaguars in Week 4.