A pair of heavyweight title holders are set to collide on Saturday night in Cardiff, Wales when unified champion Anthony Joshua collides with WBO strapholder Joseph Parker.

Joshua is getting set to make his second defense of his trio of titles while trying to adding another to his collection in a de facto semifinal in an attempt to crown an undisputed heavyweight champion.

More Joshua-Parker: Fight preview, prediction | Joshua on the verge of global stardom | Parker looking to prove his mettle

Joshua (20-0, 20 KOs) enters this fight the same way he has his previous 20 bouts: the favorite. The British knockout king will be a huge betting fave against Parker when the two enter the ring, currently going off at -700. Joshua has been a favorite of differing varieties throughout his career. He closed at -5000 against Carlos Takam last October and was a slim -200 against former heavyweight king Wladimir Klitschko in April 2017.

The number has surprisingly come down a bit from the open at -1200 for Joshua. Parker, meanwhile, will be an underdog for the first time in his career. He was a slight favorite over Hughie Fury in his latest bout last September.

Let's take a look at the latest odds for this and the rest of the fight card from Wales. The bout will begin at 5 p.m. ET and air live on Showtime.

FavoriteUnderdogWeightclass

Anthony Joshua -700

Joseph Parker +450

Heavyweight titles

Alexander Povetkin -1400

David Price +750

Heavyweight

Anthony Crolla -1400

Edson Ramirez +750

Lightweight

Joe Cordina -10000 Hakim Ben +1600 Lightweight
Josh Kelly -5000 Carlos Molina +1400 Welterweight