Duke vs. Notre Dame prediction, odds: 2022 college basketball picks, Jan. 31 best bets from proven model
SportsLine's model revealed its CBB picks and best bets for Notre Dame vs. Duke on Monday

The ninth-ranked Duke Blue Devils look to stay hot when they face the Notre Dame Fighting Irish in a key Atlantic Coast Conference showdown on Monday night. The teams enter the game tied for second place in the conference at 7-2, just one-half game behind first-place Miami at 8-2. The Blue Devils (17-3), who have won five of six, including three consecutive, have beaten Notre Dame in seven of the past eight games in the series. The Fighting Irish (14-6), who beat Duke in their last meeting, a 93-89 win on Feb. 9 of last year, have won all nine home games this season and are on a four-game winning streak. Notre Dame has won 10 of its last 11 games overall.
The game from the Joyce Center in Notre Dame, Ind., is scheduled to tip off at 7 p.m. ET. Duke is averaging 81.6 points per game, while Notre Dame averages 71.6. The Blue Devils are four-point favorites in the latest Duke vs. Notre Dame odds from Caesars Sportsbook, while the over-under for total points scored is set at 144. Before making any Notre Dame vs. Duke picks, be sure to check out the college basketball predictions and betting advice from the SportsLine Projection Model.
The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. It enters Week 12 of the season with a 49-36 record on all top-rated college basketball picks, returning almost $700. Over the past five-plus years, the proprietary computer model has generated an impressive profit of $2,800 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.
Now, the model has set its sights on Duke vs. Notre Dame, and just locked in its picks and CBB predictions. You can visit SportsLine now to see the model's picks. Here are the college basketball odds and betting lines for Notre Dame vs. Duke:
- Duke vs. Notre Dame spread: Duke -4
- Duke vs. Notre Dame over-under: 144 points
- Duke vs. Notre Dame money line: Duke -230, Notre Dame +190
- DUKE: The over is 4-0 in the Blue Devils' last four Monday games
- ND: The Fighting Irish are 7-0 against the spread in their last seven games following a straight-up win
Why Duke can cover
Freshman forward Paolo Banchero, who has scored in double digits in all 20 games and has registered five double-doubles, leads the way, but he's getting plenty of help. Sophomore center Mark Williams has been a force for the Blue Devils and is coming off his second consecutive double-double on Saturday. Against Louisville, Williams scored 14 points while grabbing 11 rebounds. It was his fifth double-double of the season and fourth in the past eight games. His best game so far was a 19-point and 11-rebound effort in an 88-73 win over North Carolina State. For the season, Williams is averaging 10.1 points, 7.1 rebounds and one assist per game.
Freshman forward AJ Griffin is off to a solid start to his collegiate career and is coming off a season-high-tying 22-point performance on Saturday. He was 8 of 13 from the field, including 5 of 5 from 3-point range. He has reached double figures in nine games this season, including another 22-point effort against Wake Forest in a 76-64 win on Jan. 12. For the year, Griffin is averaging 8.9 points, 3.2 rebounds and one assist per game on 52.1 percent shooting from the floor, including 50 percent from 3-point range, and 70.4 percent from the foul line.
Why Notre Dame can cover
The Fighting Irish also spread the wealth on offense with six players averaging 7.5 points per game or better. Junior guard Dane Goodwin tops the team in scoring, averaging 15.4 points, 4.8 rebounds and 1.2 assists per game. He has been dynamite from the field, connecting on 51.6 percent of his field goals, including 50 percent from 3-point range, making 48 of 96 attempts. He is also one of the best free-throw shooters in the nation, hitting on 88.1 percent from the foul line. Goodwin has reached double-digit scoring in all 20 games and registered one double-double, a 12-point and 11-rebound effort against High Point on Nov. 16.
Freshman guard Blake Wesley is off to a fast start to his collegiate career. He is averaging 15 points, 3.3 rebounds, 2.6 assists and 1.1 steals per game, and is connecting on 41.9 percent of his field goals, including 32.1 from 3-point range, and 67.9 percent from the free-throw line. Wesley is coming off a 14-point and seven-assist effort in Saturday's win over Virginia. He has scored in double figures in 18 of 20 games, including a season-high 24 in an 82-72 loss at Illinois on Nov. 29.
How to make Notre Dame vs. Duke picks
SportsLine's model is leaning over on the total, projecting 151 combined points. It has also generated an against-the-spread pick that cashes in well over 50 percent of simulations. You can only get the model's picks at SportsLine.
So who wins Duke vs. Notre Dame? And which side of the spread hits in well over 50 percent of simulations? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up $2,800 on its top-rated college basketball picks the last five years, and find out.















