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The No. 15 Southern California Trojans and the Stanford Cardinal will face off in a Pac-12 clash at 11 p.m. ET Thursday at the Galen Center. USC is 17-2 overall and 8-1 at home, while Stanford is 11-6 overall and 1-4 on the road. One of USC's two losses this season came against Stanford earlier this month. 

The Trojans are favored by 11 points in the latest Southern California vs. Stanford odds from Caesars Sportsbook, while the over-under is set at 142. Before entering any Stanford vs. Southern California picks, you'll want to see the college basketball predictions from the model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. It enters Week 12 of the season with a 49-36 record on all top-rated college basketball picks, returning almost $700. Over the past five-plus years, the proprietary computer model has generated an impressive profit of $2,800 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Southern California vs. Stanford. You can head to SportsLine to see its picks. Here are several college basketball odds for Stanford vs. USC:

  • Southern California vs. Stanford spread: Southern California -11
  • Southern California vs. Stanford over-under: 142 points

What you need to know about Southern California

USC will have revenge on its mind after losing to Stanford earlier this month. The Trojans were returning from a 19-day COVID-19 pause and were unable to knock off the rust. They added a loss to Oregon four days later, but they have responded with consecutive wins over Colorado, Utah and Arizona State. 

Drew Peterson led USC with 16 points and eight rebounds in Monday's 78-56 win over the Sun Devils. Junior forward Isaiah Mobley leads the team with 14.7 points and 8.7 rebounds per game. The Trojans have won 10 of their last 11 home games and are 5-0 in their last five home games against Stanford. 

What you need to know about Stanford

Stanford will bring some confidence into this matchup after upsetting USC several weeks ago. The Cardinal added a win over Washington State in their following game before losing consecutive contests to Washington and then-No. 3 Arizona. They bounced back with a 79-76 win over Arizona State last Saturday. 

This is a difficult stretch for Stanford, as it has a game against No. 7 UCLA coming up on Saturday. Freshman forward Harrison Ingram leads the Cardinal with 11.5 points and 7.1 rebounds per game. Senior forward Jaiden Delaire and junior forward Spencer Jones are both in double figures as well. 

How to make Southern California vs. Stanford picks

The model has simulated Southern California vs. Stanford 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in over 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Stanford vs. Southern California? And which side covers over 60 percent of the time? Visit SportsLine now to find out, all from the model that has crushed its college basketball picks.