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The No. 9 Oklahoma State Cowboys and the No. 22 Kansas State Wildcats will both be hoping to take another step towards the Big 12 title game when they square off on Saturday afternoon. Both teams are entering this contest with one league loss, as unbeaten TCU dealt both teams narrow losses. Kansas State is getting set to face top-10 teams in consecutive weeks for the first time since 2017, and it is also facing three top-10 teams in one season for the first time since 2014.

Kickoff is set for 3:30 p.m. ET. The Wildcats are 1.5-point favorites in the latest Kansas State vs. Oklahoma State odds from Caesars Sportsbook, while the over/under for total points scored is 56. Before entering any Oklahoma State vs. Kansas State picks, you'll want to see the college football predictions from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Kansas State vs. Oklahoma State. You can head to SportsLine to see its picks. Here are several college football odds for Kansas State vs. Oklahoma State:

  • Kansas State vs. Oklahoma State spread: Kansas State -1.5
  • Kansas State vs. Oklahoma State over/under: 56 points
  • Kansas State vs. Oklahoma State money line: Kansas State -125, Oklahoma State +105
  • Kansas State vs. Oklahoma State picks: See picks here

Why Kansas State can cover

Kansas State still controls its own destiny as far as the Big 12 title game is concerned, so the Wildcats should not lose any motivation after their loss to TCU. Their offense is powered by star running back Deuce Vaughn, who has rushed for 744 yards and four touchdowns, averaging 5.6 yards per carry. Vaughn has gone over 100 rushing yards on four occasions this season, including a 170-yard outing against Texas Tech earlier this month. 

The Wildcats have already picked up a win over then-No. 6 Oklahoma along with victories against Texas Tech and Iowa State, so they are tested and prepared for this contest. Oklahoma State has only gone on the road twice this season, with one of those outings being its loss to TCU. Kansas State has covered the spread in eight of the last 11 meetings between these teams. 

Why Oklahoma State can cover

Kansas State is dealing with some serious injury issues heading into this game, as starting quarterback Adrian Martinez had to leave last week's game with an undisclosed injury. He is questionable to return for this contest, which would be a major blow to Kansas State's chances. Junior quarterback Will Howard completed 13 of 20 passes in relief last week, but he also threw an interception. 

Oklahoma State has one of the most explosive offenses in the country, led by quarterback Spencer Sanders. He has thrown for more than 2,000 yards and 15 touchdowns, while also rushing for 352 yards and eight scores. The Cowboys have had no issue playing away from home over the past two years, covering the spread in eight straight road games. 

How to make Kansas State vs. Oklahoma State picks

The model has simulated Oklahoma State vs. Kansas State 10,000 times and the results are in. The model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 60% of simulations. You can only see the pick at SportsLine.

So who wins Kansas State vs. Oklahoma State? And which side of the spread hits in well over 60% of simulations? Visit SportsLine now to see which side of the Oklahoma State vs. Kansas State spread you need to jump on Saturday, all from the model that has crushed its college football picks, and find out.