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USATSI

The Missouri Tigers seek their second straight road victory when they visit the No. 5 Tennessee Volunteers in an SEC showdown on Saturday. Missouri (4-5, 2-4 SEC) lost its first three away games this season before upsetting then-No. 25 South Carolina 23-10 on Oct. 29. The Tigers, who dropped a 21-17 decision to Kentucky at home last week, have lost their last three meetings with the Volunteers. Tennessee (8-1, 4-1) is looking for redemption after suffering a 27-13 loss to then-No. 3 Georgia last weekend and falling from the top spot in the nation.

Kickoff at Neyland Stadium is set for noon ET. The Volunteers are 19.5-point favorites in the latest Tennessee vs. Missouri odds from Caesars Sportsbook, while the over/under for total points scored is 57. Saturday's game can be seen live on CBS and streamed live on Paramount+ with their must-have Premium plan. 

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Before making any Missouri vs. Tennessee picks, you need to see the college football predictions and betting advice from SportsLine's advanced computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Tennessee vs. Missouri and locked in its picks and CFB predictions. You can head to SportsLine now to see the model's picks. Here are several college football odds and betting lines for Missouri vs. Tennessee:

  • Tennessee vs. Missouri spread: Volunteers -19.5
  • Tennessee vs. Missouri over/under: 57 points
  • Tennessee vs. Missouri money line: Volunteers -1400, Tigers +800
  • UT: The Volunteers are 6-1 against the spread in their last seven games following a straight-up loss
  • MIZZOU: The Tigers are 2-5 ATS in their last seven meetings with the Vols
  • Tennessee vs. Missouri picks: See picks at SportsLine
  • Tennessee vs. Missouri streaming: Paramount+ 

Why Tennessee can cover

The Volunteers will be looking to take out their frustrations after last weekend's loss, which is bad news for the Tigers. Tennessee scored at least 34 points in each of its first eight games this season and produced a season-high 62 in its victory against Missouri last year. Hendon Hooker accounted for four touchdowns in the rout, throwing for three and running for another.

One of Hooker's TD passes in that meeting went to senior wideout Cedric Tillman, who was Tennessee's leading receiver against Georgia with seven catches and 68 yards. Junior Jalin Hyatt, who hauled in six passes for 63 yards versus the Bulldogs, is Hooker's No. 1 target this season as he tops the Vols with 51 receptions, 970 yards and 14 touchdown catches. Sophomore running back Jaylen Wright is first on the team with 547 rushing yards and has run for six scores, two fewer than junior Jabari Small.

Why Missouri can cover

The Tigers' record easily could be much better as each of their four losses this season have been by seven points or fewer. The club rallied from an 11-point, fourth-quarter deficit last weekend to take a 17-14 lead before giving up the decisive score with less than six minutes remaining. Sophomore quarterback Brady Cook threw for only 143 yards against the Wildcats but ran for a pair of touchdowns, tying him with senior running back Cody Schrader for the team lead in rushing scores with five.

A transfer from Truman State who led all Division II rushers last year with 2,074 yards and 24 TDs, Schrader has gained 509 yards on 111 carries this season. Dominic Lovett is Cook's top target in Missouri's passing game as he's made 45 catches for 659 yards and a pair of touchdowns. The sophomore wideout did not haul in a pass last Saturday but posted his third 100-yard performance of the season against South Carolina the previous week with a career-high 148 yards on 10 receptions.

How to make Missouri vs. Tennessee picks

SportsLine's model is leaning Over on the total, projecting a combined 58 points. The model also says one side of the spread hits well over 50% of the time. You can only see the model's CFB picks at SportsLine.

So who wins Tennessee vs. Missouri? And which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has crushed its college football picks, and find out, and don't forget to stream on Paramount+.