Western Kentucky vs. Southern Miss prediction, odds, time: 2025 New Orleans Bowl picks by proven model
SportsLine's model has revealed its Southern Miss Golden Eagles vs. WKU Hilltoppers picks for the New Orleans Bowl 2025 on Tuesday

A Tuesday college football bowl tripleheader has the Western Kentucky Hilltoppers taking on Southern Miss Golden Eagles in the middle matchup. It's the 2025 New Orleans Bowl as the former Conference USA rivals will renew acquaintances. WKU (8-4) has dropped back-to-back games, both coming by three points, while Southern Miss (7-5) is on a three-game losing streak. The Hilltoppers are 4-0 all-time versus the Golden Eagles. Blake Anderson, who was promoted from offensive coordinator to head coach, will lead Southern Miss both in this game and going forward after Charles Huff left for Memphis.
Kickoff is at 5:30 p.m. ET from the Caesars Superdome in New Orleans. After opening as slight underdogs, the Golden Eagles are now 1.5-point favorites in the latest Southern Miss vs. Western Kentucky odds, while the over/under is 58.5. Before making any Western Kentucky vs. Southern Miss picks, check out the college football predictions from the SportsLine Projection Model.
New users can target the DraftKings promo code, which offers $200 in bonus bets if your $5+ bet wins:
The model simulates every FBS game 10,000 times, and it is profitable on its top-rated money-line picks since the beginning of the 2024 season. Anybody following those college football betting picks at sportsbooks and on betting sites could have seen strong returns.
Now, the model has set its sights on Southern Miss vs. WKU. You can visit SportsLine now to see the picks. Here are the FBS college football odds and trends for WKU vs. Southern Miss:
Southern Miss vs. Western Kentucky spread | Southern Miss -1.5 at DraftKings Sportsbook |
Southern Miss vs. Western Kentucky over/under | 58.5 points |
Southern Miss vs. Western Kentucky money line | Southern Miss -125, WKU +106 |
Southern Miss vs. Western Kentucky picks | |
Southern Miss vs. Western Kentucky streaming | Fubo (Try for free) |
New users can also check out the latest FanDuel promo code and get $250 in bonus bets at FanDuel if your $5 bet wins.
How to make Western Kentucky vs. Southern Miss picks
After simulating Southern Miss vs. Western Kentucky 10,000 times, SportsLine's model is going Under on the total (57.5 points).
The Under is 6-3 over the last nine Western Kentucky games, while the Under has also hit in three out of the last four Southern Miss contests. Additionally, facing unfamiliar opponents have trended towards the total not being reached for both programs. The Under is 6-3 over WKU's last nine non-conference games, while it's 5-3 for the Golden Eagles when playing out-of-conference opponents.
While both teams are projected to pile up heavy yardage, that doesn't necessarily mean lots of points due to the turnover factor. The teams are projected to combine for 3.5 turnovers, on average, which stunts many drives. With that, the game is forecasted to hit the Under more than 60% of the time.
The model also says one side of the spread hits well over 60% of the time. You can see the model's pick at SportsLine.
So who wins Western Kentucky vs. Southern Miss, and which side of the spread hits well over 60% of the time? Visit SportsLine now to see which side of the Southern Miss vs. Western Kentucky spread to jump on, all from the advanced model that's up on its top-ranked money-line picks, and find out.
















