Thompson was released from the 49ers' practice squad Tuesday, David Lombardi of The Athletic reports.

The 30-year-old was added to the team's practice squad Sept. 22 as a result of injuries in the backfield. Now that Elijah Mitchell (shoulder) is nearing a return and the 49ers' no longer need additional running back depth, Thompson was the odd man out. He appeared in eight games for the Jaguars in 2020, notably catching 20 balls for 146 yards and a touchdown.

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