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Tyjae Spears RB | TEN
Titans' Tyjae Spears: Questionable after full practice
Spears (knee) is listed as questionable for Sunday's game against the Jaguars after upgrading to full practice participation Friday, Jim Wyatt of the Titans' official site reports.
A return to action after missing two games would hurt Tony Pollard's workload projection, though Pollard would still be in line for most of the carries. There have also been hints of rookie Nicholas Singleton getting playing time in the second half of the season, leaving Spears without much of a path to mainstream fantasy value.
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Devin Singletary RB | NYG
Giants' Devin Singletary: Plays just five snaps
Singletary played just five snaps on offense and took one carry for three yards in Sunday's 24-21 loss to the Commanders.
Cam Skattebo came back from a hamstring injury and dominated backfield work, taking 21 touches for 122 yards and two touchdowns on an 88 percent snap share. Singletary played 92 percent of snaps the week before in a win at Philadelphia, but his 23 touches went for just 39 total yards and no TD. It'll likely be another large workload for Skattebo when the Giants host the Jaguars in Week 11.
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Andrei Iosivas WR | CIN
Bengals' Andrei Iosivas: Doubtful to be activated
Iosivas (thumb) is listed as doubtful for Sunday's game against Pittsburgh.
Iosivas returned to practice Thursday and was a full participant both Thursday and Friday. He should be ready for Week 11, at which point he'll likely take the No. 3 WR job back from Dohnte Meyers.
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Kenneth Walker III RB | KC
Chiefs' Kenneth Walker: Deemed questionable for Sunday
Walker (groin) is listed as questionable for Sunday's game against the Falcons.
Walker was added to the Chiefs' Week 10 injury report due to groin tightness that kept him from practicing Friday. Now that he's carrying an official 'questionable' designation heading into the weekend, the running back's status will need to be tracked as Sunday's 1:00 pm ET kickoff approaches. In the event that Walker -- who is averaging a robust 109.0 rushing yards per game and has scored 11 total TDs through eight contests -- is made inactive for the contest, Emmett Johnson would be in line to handle the bulk of the team's carries versus Atlanta.
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T.J. Hockenson TE | MIN
Vikings' T.J. Hockenson: Not spotted Friday
Hockenson (wrist/chest) wasn't seen during the portion of Friday's practice open to the media, Kevin Seifert of ESPN.com reports.
Hockenson appears set to go down as a non-participant for a third consecutive practice due to wrist and chest issues, and the Vikings now may make a ruling on his status for Sunday's game in Green Bay on their final Week 10 injury report Friday. If Hockenson is inhibited or sidelined this weekend, Ben Yurosek and Gavin Bartholomew are the other tight ends on the active roster, while Devin Culp can be elevated from the practice squad.
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CJ Donaldson RB | NO
Saints' CJ Donaldson: Out this week
Donaldson (shoulder) has been ruled out for Sunday's game against the Panthers, Nick Underhill of NewOrleans.Football reports.
Donaldson will miss a third straight game, while Travis Etienne (hamstring) has a chance to return from injured reserve. With Etienne listed as questionable, Audric Estime and Alvin Kamara could have significant roles. Donaldson mostly has played in obvious passing situations this year, often staying in as a blocker.
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Zachariah Branch WR | ATL
Falcons' Zachariah Branch: Out again this week
Branch (hamstring) has been ruled out for Sunday's game against the Chiefs.
Branch missed a Week 9 loss to the Bengals and didn't practice this week. Olamide Zaccheaus and Chris Blair took on extra snaps in Branch's absence last week. The good news for Branch is that Atlanta has a bye coming up after Sunday's game.
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Travis Etienne RB | NO
Saints' Travis Etienne: May return in Week 10
Etienne (hamstring) said Friday that "the week of practice went well," and that he hopes to be active for Sunday's game against the Panthers, Jeff Nowak of WWL Radio reports.
Etienne remains on injured reserve and officially is listed as questionable for Week 10, per Ross Jackson of WWL-TV. After the Saints designated Etienne for return from IR on Wednesday, he opened the week with back-to-back limited sessions before logging a full practice Friday, but the team still will need to activate him by Saturday afternoon for him to have a chance to play Sunday. With CJ Donaldson (shoulder) ruled out, Alvin Kamara and Audric Estime will be the other RBs to vie with for touches if Etienne is able to suit up this weekend.
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Josh Downs WR | KC
Chiefs' Josh Downs: Likely playing Sunday
Chiefs coach Andy Reid said Friday that Downs looks ready to play in Sunday's game at Atlanta, Charles Goldman of AtoZ Sports reports.
The Chiefs traded for Downs on Tuesday before the deadline and had him on the practice field by Wednesday. Reid stopped short of saying Downs will play, but it sounds like the wideout will have some kind of role this Sunday alongside Rashee Rice and Xavier Worthy.
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Emmett Johnson RB | KC
Chiefs' Emmett Johnson: Could lead backfield Sunday
Coach Andy Reid noted that Johnson would take the bulk of the Chiefs' carries in the event that Kenneth Walker -- who didn't practice Friday due to groin tightness -- is forced to miss Sunday's game against the Falcons, Pete Sweeney of The Kansas City Star reports.
Added context regarding Walker's status will arrive via Friday's final injury report when the Chiefs assign their Week 10 injury designations. Chances are, Walker will be deemed questionable, but if he ends up sidelined this weekend, Johnson would provide those who roster Walker, or otherwise need RB help, with a viable pivot option.