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The San Francisco Giants and New York Mets were originally scheduled to open their series on Monday, but that game was postponed due to rain. The Giants will instead be looking to extend their five-game winning streak on Tuesday afternoon before these teams meet again later in the day. New York is in excellent form to open the season as well, winning four of its last five games. These teams met for a three-game series last August, with San Francisco winning all three contests. 

First pitch for Game 1 of the doubleheader is set for 3:10 p.m. ET from Citi Field in New York. New York is the slight -125 favorite (risk $125 to win $100) in the latest Mets vs. Giants odds from Caesars Sportsbook, with the over-under set at seven runs. Before making any Giants vs. Mets picks, you need to check out the latest MLB predictions and betting advice from the SportsLine Projection Model.

The model, which simulates every MLB game 10,000 times, is off to a sizzling start to the 2022 season. It's on a 14-4 roll on top-rated MLB money-line picks through two weeks, returning over $800 for $100 players. Anyone following it has seen HUGE returns!  

Now, the model has locked in on Giants vs. Mets, and just locked in its picks and MLB predictions. You can visit SportsLine now to see the model's picks. Here are the MLB odds and trends for Mets vs. Giants:

  • Giants vs. Mets money line: New York -125, San Francisco +105
  • Giants vs. Mets run-line:  New York -1.5 (+175)
  • Giants vs. Mets over-under: 7 runs 
  • NYM :Mets are 8-2 ATS this season
  • SF: Giants are 4-5 ATS this season

Why you should back the Mets

New York's pitching prowess has been on full display so far this season, even though the Mets are without ace Jacob deGrom. They have won four of their last five games and have already recorded three shutouts in 2022. Tuesday afternoon's starter, Tylor Megill, has fired two of those shutouts, including 5.1 scoreless innings at Philadelphia his last time out. 

Megill has given up just three hits in each of his first two starts, so he is going to be brimming with confidence entering this game. New York also has more offensive firepower than San Francisco, as the Mets lineup includes Pete Alonso, Francisco Lindor and Mark Canha. They have covered the spread in eight of their 10 games this season, making them a strong wagering option on Tuesday afternoon. 

Why you should back the Giants

San Francisco might be the hottest team in the MLB, bringing a five-game winning streak into this contest. The hot streak includes a 13-2 win over San Diego and an 8-1 blowout over Cleveland. Starting pitcher Alex Cobb was sharp in his first outing of the season, allowing two earned runs across 5.0 innings against San Diego.  

Cobb is a veteran, so he is not going to be distracted by having the start time of his game moved up. Meanwhile, Megill is 0-1 with a 7.45 ERA in two career starts against the Giants. San Francisco has won six of the last seven meetings between these teams and is 15-2 in its last 17 road games. 

How to make Mets vs. Giants picks

SportsLine's model is leaning over on the run total, as the simulation suggests the teams will combine for 9.3 runs. It also says one side of the money line has all the value. You can only get the model's pick at SportsLine

So who wins Giants vs. Mets? And which side of the money line has all the value? Visit SportsLine now to see which side to jump on, all from the advanced model that has crushed its top-rated MLB picks, and find out.