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With the new and improved bet365 promo code CBSBET365, you can get $300 in bonus bets instantly for online sports betting. The 2025 MLB playoffs are right around the corner, and there are still a handful of divisions and wild card spots that are still being fiercely contested. The Seattle Mariners are clinging to an AL Wild Card bid as they head into a Tuesday night matchup with the St. Louis Cardinals, who are fading in the NL Wild Card race, and that's one of several matchups with at least some playoff implication. 

The pitching matchup will be George Kirby vs. Matthew Liberatore, and the latest MLB odds from bet365 list the Mariners as -205 favorites on the money line, while the over/under is 7.5 runs. With both starting pitchers sporting ERAs above 4.00, the SportsLine Projection Model is recommending over 7.5 runs (-105) as one of its MLB best bets for Tuesday. Kirby's over/under for total strikeouts is 5.5, while Liberatore's over/under for total outs recorded is 15.5. Before locking in your Tuesday MLB picks on your favorite betting sites like bet365, be sure to check out the rest of the top MLB betting picks from SportsLine's proven computer model. Click here to get the newest bet365 bonus code and take advantage of one of the best sportsbook promos:  

The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 25 of the 2025 MLB season a profitable 34-25 on top-rated MLB money-line picks. It has excelled making home run prop picks this season, returning more than 60 units of profit. Anybody following its MLB betting picks at sportsbooks and on betting sites could have seen strong returns.

Best Tuesday MLB picks for bet365: 

Combining the model's three picks into a Tuesday MLB parlay at bet365 would result in a payout of +603 (risk $100 to win $603). Bet it at bet365 here:

Mariners vs. Cardinals Over 7.5 total runs (-105)

Liberatore and Kirby are both former first-round picks with solid stuff, but they've each had a rough go of it lately. Liberatore hasn't registered a quality start since June and Kirby surrendered seven earned runs on 10 hits in just two innings of work his last time out to have his ERA to swell from 3.71 to 4.47 over his last four starts alone. Both teams have quality bullpens but are still in the playoff race to some extent and won't want to exhaust those resources downt he stretch. The model predicts that the over hits in 65% of simulations. Bet it now at bet365 and get $300 in bonus bets win or lose after your first $5 wager.

Nationals (+100) to defeat the Marlins

Both teams are out of the MLB playoff picture, so it's really about matchup history, and Nationals starter Mitchell Parker -- despite a 5.87 ERA on the season -- has been solid throughout his career against the Marlins. In six career starts against Miami, he's posted a 3.86 ERA, which is by far his best mark against any of the four teams he's made at least four career starts against. Meanwhile, Marlins starter Adam Mazur is making just his fourth start of the year, has a 5.73 ERA over 15 1/3 innings this season, and has a 6.93 career ERA. The Nationals win outright in 52% of simulations, so jump on this price from bet365 to get $300 in bonus bets after your first $5 wager.

Guardians (-125) to defeat the Royals

Both teams are on the fringe of the AL Wild Card discussion and are hoping to play their way back into contention over the final three weeks of the season. However, it's Cleveland that is playing better of late, winning six of its last 10 games while Kansas City is 4-6 over its last 10 outings. Lefties Noah Cameron and Joey Cantillo have both been solid this season, and both teams rank bottom-four in the league in run production, so expect a low-scoring battle. Ultimately, the model has Cleveland winning in 60% of sims. Use the bet365 promo code CBSBET365 for $300 in bonus bets or a $1,000 safety net on your first wager.

Want more MLB picks for Tuesday, September 9?

You've seen the model's Tuesday MLB best bets. Now, get against the spread, total and money-line picks for Tuesday MLB games, along with the Week 2 NFL schedule and college football, all from the model that's simulated every game 10,000 times. 

Also at SportsLine:

You can also see Tuesday MLB picks from SportsLine expert Bruce Marshall, who is 138-125-3 (+2433) over his last 266 MLB picks. He's already locked in an MLB pick for Tuesday. See his best bets right here.