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Wells Fargo Center hosts a 2023 NBA In-Season Tournament matchup between the Philadelphia 76ers and the Cleveland Cavaliers on Tuesday. Cleveland is 7-6 overall and 4-3 on the road this season, with Philadelphia entering at 10-3 overall and 6-2 at home. Kelly Oubre Jr. (rib) is out of action for the 76ers. Donovan Mitchell (hamstring) and Isaac Okoro are out for the Cavaliers, with Caris LeVert (knee) listed as questionable.

For this game, SportsLine consensus lists the Sixers as 7.5-point favorites, and tip-off is scheduled for 7:30 p.m. ET. The total number of points Vegas thinks will be scored, or the over/under, is 219 in the latest Cavaliers vs. 76ers odds. Before making any 76ers vs. Cavaliers picks, you'll want to see the NBA predictions from SportsLine's proven model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past five seasons. The model enters Week 5 of the 2023-24 NBA season on a 82-46 roll on all top-rated NBA picks dating back to last season, returning more than $3,000. Anyone following it has seen huge returns.

The model has set its sights on Cavs vs. Sixers and locked in its NBA predictions. You can head to SportsLine to see its picks. Here are several NBA odds and betting lines for Sixers vs. Cavs:

  • Cavaliers vs. 76ers spread: 76ers -7.5
  • Cavaliers vs. 76ers over/under: 219 points
  • Cavaliers vs. 76ers money line: 76ers -320, Cavaliers +250
  • CLE: The Cavaliers are 5-8 against the spread this season
  • PHI: The 76ers are 10-3 against the spread this season
  • Cavaliers vs. 76ers picks: See picks at SportsLine

Why the Cavaliers can cover

Cleveland is dealing with the absence of Mitchell, but the Cavaliers have a top-tier guard in Darius Garland. He is averaging 21.5 points and 8.0 assists per game over the last three years, and Garland is shooting 39.3% from 3-point range over that sample. Garland headlines an offense that is averaging 15.4 fast break points per game this season, and the Cavaliers are firmly in the top 10 of the league in 2-point accuracy (55.6%), free throw creation (23.6 attempts per game), turnovers (13.9 per game) and points in the paint (53.1 per game). 

On defense, Cleveland's rim protection is top notch with Evan Mobley and Jarrett Allen. The Cavaliers lead the league in 2-point defense, giving up only 49.6% shooting, and Cleveland is also in the top five in opponent field goal percentage (45.3%). Cleveland is also giving up only 45.2 points in the paint per game, a figure near the top of the NBA. See which team to pick here. 

Why the 76ers can cover

The 76ers are flying high on offense this season, scoring more than 1.2 points per possession. Philadelphia is shooting 48.3% from the field and 37.8% from 3-point range, and the 76ers are in the top eight of the league in turnovers (13.2 per game) and offensive rebound rate (31.2%). Philadelphia is leading the NBA with 19.0 fast break points per game, and the 76ers are in the top five with 55.7 points in the paint per game. The 76ers are also tremendous at the free throw line, leading the NBA in accuracy (86.7%) and landing in the top three in free throw creation (26.7 per game).

Philadelphia also has top-10 marks in opponent shooting and defensive rebound rate, and the 76ers are led by a pair of tremendous contributors. Reigning NBA MVP Joel Embiid is leading the NBA with 31.9 points per game, and he is averaging 11.2 rebounds and 6.2 assists per contest. Tyrese Maxey is putting up 26.8 points and 7.1 assists per game, and he is enjoying his strongest performance of any season in his young career. See which team to pick here.

How to make 76ers vs. Cavaliers picks

The model has simulated Cavs vs. 76ers 10,000 times and is leaning Over the total, projecting 219 combined points. It also says one side of the spread is the better value. You can only see the picks at SportsLine. 

Who wins Cavs vs. 76ers, and which side of the spread is the better value? Visit SportsLine now to see the picks, all from the model that is on a 82-46 roll on top-rated NBA picks, and find out.