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The San Antonio Spurs will take on the Charlotte Hornets at 8:30 p.m. ET on Wednesday at the AT&T Center. San Antonio is 10-16 overall and 6-8 at home, while Charlotte is 15-14 overall and 7-10 on the road. The Spurs are wrapping up a five-game homestand and the Hornets are playing the second game of a six-game road trip. 

San Antonio is favored by 3.5-points in the latest Spurs vs. Hornets odds from Caesars Sportsbook, while the over-under is set at 228. Before entering any Hornets vs. Spurs picks, you'll want to see the NBA predictions from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit on its top-rated NBA picks over the past three-plus seasons. The model enters Week 9 of the 2021-22 NBA season on a stunning 44-20 roll on all top-rated NBA picks, returning over $2,000. Anyone following it has seen huge returns.

Now, the model has set its sights on Spurs vs. Hornets. You can head to SportsLine to see its picks. Here are several NBA betting lines for Spurs vs. Hornets:

  • Spurs vs. Hornets spread: Spurs -3.5
  • Spurs vs. Hornets over-under: 228 points

What you need to know about the Spurs

San Antonio is wrapping up a five-game homestand on Wednesday night. The Spurs have split the first four games and are coming off a 112-97 win over New Orleans on Sunday. Jakob Poeltl and Derrick White each scored 24 points in the victory, while Dejounte Murray had a triple-double. 

San Antonio has won two of its past three games and owns a 42-20 all-time advantage over Charlotte. The Spurs have won 12 of the last 14 head-to-head meetings in Texas. They are also on fire against the spread right now, covering in seven of their last nine games. 

What you need to know about the Hornets

Charlotte will be playing the second game of a six-game road trip following a 120-96 loss to Dallas on Monday. The Hornets were in a tough position by the half, with the score already sitting at 70-43. They have been dealing with COVID-19 absences, as Mason Plumlee, Jalen McDaniels, LaMelo Ball and Ish Smith were all out on Monday. 

Guard Terry Rozier had missed four straight games, but he returned to score 20 points in the loss. Plumlee and McDaniels are expected to be available on Wednesday night. The Hornets have covered the spread in five of their last six games and are 4-2 ATS in their last six games against San Antonio. 

How to make Spurs vs. Hornets picks

The model has simulated Spurs vs. Hornets 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in almost 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Hornets vs. Spurs? And which side of the spread hits almost 60 percent of the time? Visit SportsLine now to find out which side of the spread you need to jump on Wednesday, all from the model that has crushed its NBA picks, and find out.