Bengals vs. Panthers prediction, odds, line, spread: 2022 NFL picks, Week 9 best bets from advanced model
SportsLine simulated Carolina Panthers vs. Cincinnati Bengals 10,000 times and made its Week 9 NFL picks, predictions, and best bets

Joe Burrow and the Cincinnati Bengals (4-4) are looking to bounce back from an embarrassing 32-13 loss to the Cleveland Browns on Monday Night Football in Week 8. They will be hosting P.J. Walker and the Carolina Panthers (2-6) at Paycor Stadium in Cincinnati. The Panthers are also looking to rebound from a disappointing 37-34 overtime loss to the Atlanta Falcons. Carolina is 3-5 against the spread, while Cincinnati is 5-3 ATS in 2022.
Kickoff is at 1 p.m. ET. Cincinnati is favored by 7 points in the latest Bengals vs. Panthers odds from Caesars Sportsbook, and the over/under is set at 42.5. Before making any Panthers vs. Bengals picks, you need to see the NFL predictions and betting advice from the proven simulation model at SportsLine.
The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 9 of the 2022 NFL season on an incredible 148-107 run on top-rated NFL picks that dates back to the 2017 season. The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.
Now, the model has set its sights on Bengals vs. Panthers and just locked in its picks and NFL Week 9 predictions. You can head to SportsLine now to see the model's picks. Here are several NFL odds and betting lines for Panthers vs. Bengals:
- Bengals vs. Panthers spread: Bengals -7
- Bengals vs. Panthers over/under: 42.5 points
- Bengals vs. Panthers money line: Cincinnati -345, Carolina +270
- Bengals vs. Panthers picks: See picks here
What you need to know about the Bengals
The Bengals have been the definition of inconsistency in 2022. At times they've looked like a team fully capable of defending their AFC Championship from a year ago, and at other times they've had the look of a team destined to land a top-10 pick in the 2023 NFL Draft. Their matchup with the Panthers will provide some opportunity to salvage their season, but it will likely come down to the play of their offensive line.
In addition to their offensive line issues, it quickly became clear how important wide receiver Ja'Marr Chase is to the Cincinnati offense. Chase will be out for 4-6 weeks as he recovers from a hip injury, so the team will be relying on increased production from fellow wide receivers Tee Higgins and Tyler Boyd.
What you need to know about the Panthers
Carolina fought into overtime against the Atlanta Falcons this past Sunday but ultimately fell 37-34. The Panthers had a chance to potentially win the game in regulation, but an unsportsmanlike penalty on wide receiver D.J. Moore made Carolina's go-ahead PAT attempt 15 yards more difficult, and kicker Eddy Pineiro ultimately missed the kick. RB D'Onta Foreman put forth a good effort for the losing side as he rushed for three TDs and 118 yards on 26 carries.
Walker is making his third consecutive start for Carolina with Baker Mayfield listed as a healthy scratch. Walker, a former XFL star, turned in an impressive performance against the Falcons, completing 19 of 36 passes for 317 yards, one touchdown, and one interception. He added 20 yards on the ground as well.
How to make Bengals vs. Panthers picks
The model has simulated Panthers vs. Bengals 10,000 times and the results are in. The model is leaning Over on the point total, and it also says one side of the spread has all the value. You can only see the model's pick at SportsLine.
So who wins Bengals vs. Panthers? And which side of the spread has all the value? Visit SportsLine right now to find out which side of the Panthers vs. Bengals spread you should be all over, all from the model on a 148-107 roll on its top-rated NFL picks, and find out.















