Bills vs. Falcons odds, line: 2022 NFL picks, Week 17 predictions from proven computer model
SportsLine's model just revealed its NFL picks for Falcons vs. Bills

The Atlanta Falcons will take on the Buffalo Bills at 1 p.m. ET on Sunday at Highmark Stadium. Buffalo is 9-6 overall and 4-3 at home, while the Falcons are 7-8 overall and 5-3 on the road. Buffalo is aiming for a third consecutive win. Atlanta has won two of its past three games.
The Bills can clinch a playoff berth with a win and a loss by Baltimore, the Chargers, or Raiders. Buffalo is favored by 14.5 points in the latest Bills vs. Falcons odds from Caesars Sportsbook, and the over-under is set at 44. Before entering any Falcons vs. Bills picks, you'll want to see the NFL predictions from the model at SportsLine.
The model, which simulates every NFL game 10,000 times, is up over $7,100 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 17 of the 2021 season on an incredible 134-96 run on top-rated NFL picks that dates back to the 2017 season.
The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.
Now, the model has set its sights on Bills vs. Falcons. You can head to SportsLine to see its picks. Here are several NFL betting lines for Falcons vs. Bills:
- Bills vs. Falcons spread: Bills -14.5
- Bills vs. Falcons over-under: 44 points
What you need to know about the Bills
Buffalo picked up a a 33-21 victory over the New England Patriots last Sunday. Josh Allen passed for three TDs and 314 yards on 47 attempts in addition to picking up 64 yards on the ground. It was his fifth career game with 300-plus passing yards and 50-plus rushing yards, second-most in NFL history. Stefon Diggs caught a TD pass for the third consecutive game.
Devin Singletary has rushed for a TD in two straight games. Ed Oliver (ankle) and Emmanuel Sanders (knee) are questionable for Sunday's game.
What you need to know about the Falcons
Meanwhile, Atlanta beat Detroit last Sunday, 20-16. Matt Ryan threw a tie-breaking TD pass to Hayden Hurst early in the final quarter. Foye Oluokun's interception with 33 seconds left in the game sealed the victory. The Falcons won for the first time at Mercedes-Benz Stadium this season.
Fabian Moreau (ribs) is doubtful for Sunday's game. Hurst, Richie Grant, and Tajae Sharpe are among the Atlanta players in the league's health and safety protocols.
How to make Falcons vs. Bills picks
The model is leaning over on the total, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. You can only see the pick at SportsLine.
So who wins Bills vs. Falcons? And which side of the spread hits more than 50 percent of the time? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks.















