NFL Week 15 odds, predictions, expert picks: Who gets the edge in Packers-Broncos? Can Lions upset Rams?
CBS Sports and SportsLine break down Week 15's late slate of games, plus SNF and MNF
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6 min read
Week 15 is one of those weeks you long for in the summer months when football is still a ways away. The NFL has a jam-packed slate this weekend, filled to the brim with high-stakes matchups. On top of the sheer amount of fantastic games, playoff implications are on the line no matter which way you look.
Some clinching scenarios for Week 15 include the New England Patriots potentially clinching the AFC East if they beat the Buffalo Bills, while both the Los Angeles Rams and Denver Broncos can secure their postseason spots with wins. All that makes it a wonderful weekend to sit back, relax and bet on the NFL.
As we do every week throughout the season, we've collected all of the best picks and gambling content from CBS Sports and SportsLine and put them in one convenient place, so you can get picks against the spread from our CBS Sports experts as well as additional feature content for each game, including plays from top SportsLine experts and the SportsLine Projection Model, best bets from our staff, survivor picks and more. Ready? Let's jump in.
All NFL odds via DraftKings Sportsbook.
Panthers at Saints
Sunday, 4:25 p.m. on Fox (Stream: Fubo -- try for free)
Saints +2.5: "The Panthers are off their bye, while the Saints are back home after two on the road. The Saints beat the Panthers in Week 10, but this Panthers team has been playing much better football lately. Saints quarterback Tyler Shough is playing well and the New Orleans defense can keep them in this one. Saints win it in an upset." -- CBS Sports Senior NFL analyst Pete Prisco on why he has New Orleans upsetting Carolina at home. To see all of Prisco's Week 15 picks, click here.
Lions at Rams
Sunday, 4:25 p.m. on Fox (Stream: Fubo -- try for free)
Rams -5.5: "If the Rams can turn this into a shootout, I'm not sure the Lions will be able to keep up and that's mostly because I expect Goff to be running for his life for all four quarters. The Lions are 4-0 this year in games where Goff doesn't get sacked, but it's going to be hard to keep him clean in a game against a Rams defense that's averaging 2.8 sacks per game, which is the sixth-highest total in the NFL. The Rams just don't have a lot of holes right now, which makes it almost impossible to pick against them." -- CBS Sports NFL writer John Breech on why he likes L.A. to cruise to the 30-21 victory over Detroit. To see the rest of his Week 15 picks, click here.
Packers at Broncos
Sunday, 4:25 p.m. on CBS (Stream on Paramount+)
Broncos +2.5: "We've seen duds from Green Bay at various points this season, and I wonder if we get one here -- particularly on the road in a tough environment against one of the best defenses in the NFL. What Denver does well is attacking the quarterback while protecting its own, ranking No. 1 in the league in sacks (55) this season, as well as being tied for the fewest sacks allowed (17). If Bo Nix has a clean pocket while Jordan Love is under constant pressure, that could open the door for an upset. The Broncos are also a perfect 6-0 straight-up at home this season." -- CBS Sports NFL writer Tyler Sullivan on why he has Denver upsetting Green Bay at home. To see the rest of his Week 15 picks, click here.
Packers -2.5: "Green Bay has won four in a row and seems to be hitting its stride on both sides of the ball. The passing game has seemingly gotten on track over the last few weeks, and we know what they can do defensively. The Broncos can reach as high a ceiling defensively as any team in the NFL, but they also have a low floor offensively, and I'm not as confident in Bo Nix against the Green Bay pass rush as I am in Jordan Love against Denver's." -- CBS Sports NFL writer Jared Dubin on why he likes Green Bay to win on the road, 23-20. To see his best bets for Week 15, click here.
Colts at Seahawks
Sunday, 4:25 p.m. on CBS (Stream on Paramount+)
Seahawks -13.5: "If it's Rivers, Sunday will mark 1,800 days between starts. Of course, that's a lot of time, and expecting Rivers to somehow keep it close against a Seattle defense that is second in the league in points per game allowed (17.4), yards per play allowed (4.5) and third down (33% conversion rate) seems too tall a task. As interesting as Rivers' comeback story is right now, it could be spoiled by halftime and downright sad by the fourth quarter." -- CBS Sports NFL writer Tyler Sullivan on why he likes Seattle to cover over Indy, 30-16. To see the rest of his Week 15 picks, click here.
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Titans at 49ers
Sunday, 4:25 p.m. on Fox (Stream: Fubo -- try for free)
49ers -12.5: "This is consecutive road games for the Titans coming off a road victory at Cleveland. The 49ers are off a bye. That's a bad combination and San Francisco is in a playoff chase, while the Titans are playing out the string. Oh, and the 49ers are much better. Look for a big 49ers victory." -- CBS Sports Senior NFL analyst Pete Prisco on why he likes the Niners to take down the Titans, 32-17. To see all of Prisco's Week 15 picks, click here.
Vikings at Cowboys
Sunday, 8:20 p.m. on NBC (Stream: Fubo -- try for free)
Look no further than SportsLine's R.J. White if you want to gain the edge in Vikings-Cowboys. White is currently on a 37-17-3 roll (+1882) on his last 57 picks involving Minnesota, making him a go-to source for this "Sunday Night Football" showdown. We can tell you White is leaning Under the 48-point total, but to see his official best bet as he looks to improve his stellar record, you'll need to click over to SportsLine.
Cowboys -5.5: "I was very wrong about how the Vikings would fare against the Washington Commanders last week, but we've seen this movie before. Remember when the Vikings went and upset the Lions in Week 9? Everyone thought Minnesota had turned a corner. Then, the Vikings lost four straight with horrific quarterback play. While the Cowboys lost to the Lions in Week 14, they had a mini bye to rest, and are surely rejuvenated by the rival Eagles' overtime loss to the Chargers on "Monday Night Football." To put it simply, Dak Prescott is going to out-score J.J. McCarthy. " -- CBS Sports' Jordan Dajani on why the Cowboys will win and cover over the Vikings. To see the rest of his Week 15 picks, click here.
Dolphins at Steelers
Monday, 8:15 p.m. on ESPN (Stream: Fubo -- try for free)
Having trouble formulating a pick for Monday night? Let R.J. White be of assistance. The SportsLine expert has been on a tear when it comes to betting games involving the Pittsburgh Steelers, owning a 37-20-1 record over his last 58 picks. We can tell you White is leaning Under the 42-point total, but to see his official play for this game, head over to SportsLine.
Dolphins +3: "The Dolphins' high-powered rushing attack will now get to face a Steelers defense that has given up more than 200 yards rushing in two straight games. In Week 13, the Bills kept running the same play against the Steelers because it kept working. If Mike McDaniel can find a running play that works, I could see him running it 60 straight times. De'Von Achane is going to be the x-factor here. He got banged up with a rib injury against the Jets in Week 14 and if he can't play, that will be a huge hit for Miami, but for now, I'm going to say the Dolphins finally do the impossible and win a cold-weather game." -- CBS Sports NFL writer John Breech on why he likes Miami to pull off the 19-16 upset over the Steelers. To see the rest of his Week 15 picks, click here.
