The Oakland Raiders will take on the Indianapolis Colts at 1 p.m. ET on Sunday at Lucas Oil Stadium. Indianapolis is 2-1 overall and 1-0 at home, while Oakland is 1-2 overall and 0-1 on the road. The Raiders have struggled mightily after winning their opening game, blowing a 10-0 lead against the Chiefs in Week 2 and then getting dismantled 34-14 by the Vikings last week. The Colts, meanwhile, enter Sunday's showdown having won each of their last two games. Indianapolis is favored by 6.5-points in the latest Raiders vs. Colts odds, while the over-under is set at 45. Before you make any Raiders vs. Colts picks and NFL predictions for Week 4, you'll want to see what the SportsLine Projection Model is saying.

The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on its top-rated NFL picks since its inception four years ago. It has nailed its recent top-rated NFL picks, entering Week 4 of the 2019 season on a strong 17-10 run. It's also on a 79-53 roll on top-rated NFL against the spread picks that dates back to the 2017 season. And in Week 3, it was all over the Saints (+5) without Drew Brees covering against the Seahawks and Daniel Jones leading the Giants (+5) to the cover against the Bucs. The model also ranked in the top 10 on NFLPickWatch for the third year in a row on straight-up NFL picks and beat more than 96 percent of CBS Sports office pool players. Anyone who has followed it is way up.

Now, it has simulated Colts vs. Raiders 10,000 times and the results are in. We can tell you that the model is leaning under, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. You can only see the pick at SportsLine.

The model knows how well Indianapolis plays at Lucas Oil Stadium, as the Colts are 7-0 in their last seven games at home. Colts quarterback Jacoby Brissett and his offense are finding their rhythm, having scored 24 or more points in two of their first three games this season. Last week against the Falcons, Brissett threw for 310 yards and two touchdowns and finished with a 118.1 passer rating. Running back Marlon Mack also played extremely well against Atlanta, finishing with 16 carries for 74 yards and a touchdown. Now, the Colts' offense will look to exploit an Oakland defense that is giving up 398.7 yards per game, which ranks 25th in the NFL.

Oakland, meanwhile, has to be hurting after a devastating 34-14 defeat at the hands of Minnesota. The Raiders were unable to get anything going through the first three quarters and entered the fourth quarter trailing 28-7. However, tight end Darren Waller was a bright spot for Oakland's offense against the Vikings, finishing with 13 receptions for 134 yards. For the season, Waller has 26 receptions for 267 receiving yards and he'll hope to find the end zone this week against the Colts, who gave up two touchdowns to tight end Austin Hooper last week.

Oakland is 7-3 against the spread in its last 10 games against Indianapolis. However, the Colts are 12-3 in their last 15 games and 6-2-1 against the spread in their last nine. 

So who wins Colts vs. Raiders? And which side of the spread is hitting in over 50 percent of simulations? Visit SportsLine right now to see which side of the Raiders vs. Colts spread you need to jump on, all from the computer model that has crushed its NFL picks.