Alford (ankle) is questionable to return against the Patriots on Sunday, Lance Lysowski of The Buffalo News reports.
Alford sustained the injury in the second half of Sunday's game, and he's being evaluated by trainers to determine whether he can return. Davison Igbinosun should see more defensive snaps in Alford's absence.
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Bills' Ed Oliver: Leaves game with knee injury
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Oliver (knee) is questionable to return against the Patriots on Sunday, Lance Lysowski of The Buffalo News reports.
With Oliver being evaluated by medical staff and T.J. Sanders (appendix) inactive, the Bills will lean more heavily on DeWayne Carter, Landon Jackson and Greg Gaines on defense.
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Bills' Te'Cory Couch: Likely done for remainder of Week 4
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Couch suffered a hamstring injury Sunday versus New England and is doubtful to return.
Couch was a practice-squad elevation for Week 4. He was slated to potentially pick up some work on defense with Christian Benford (toe) inactive, but now Couch is probably done for the day. With that said, Couch's likely absence will primarily impact Buffalo's special-teams unit.
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Bills' Davison Igbinosun: Set to start in Week 4
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Igbinosun is expected to start in Sunday's game against the Patriots, Chris Brown of the Bills Radio Network reports.
Igbinosun will get the start for the Bills on Sunday with Christian Benford out with a toe injury. In 30 snaps on defense in Week 3, the 22-year-old recorded six tackles (three solo). He will play opposite Maxwell Hairston and Dee Alford.
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Bills' T.J. Sanders: Inactive versus Patriots
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Sanders (appendix) is inactive for Sunday's game against the Patriots.
Sanders is still healing from appendix surgery on Tuesday, Sep. 22, though he did return to practice Thursday. Landon Jackson may get more playing time alongside Ed Oliver and Deone Walker while Sanders is out.
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Bills' Christian Benford: Will miss Week 4
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Benford (toe) is inactive for Sunday's game against the Patriots.
The fourth-year pro was absent from practice heading into Sunday's game after exiting in the third quarter of the Patriots' Week 3 loss to Jacksonville. Davison Igbinosun is expected to see more playing time with Benford out.
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Bills' Christian Benford: Unable to practice so far this week
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Benford (toe) did not participate in practice Wednesday or Thursday.
Benford suffered a toe injury during the third quarter of Sunday's Week 3 win over the Chargers and didn't return to the contest. With consecutive DNPs to begin the week of prep, the veteran cornerback's status for Sunday's matchup against the Patriots is looking very iffy. Should Benford not be able to suit up for that game, Davison Igbinosun could draw the start.
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Bills' T.J. Sanders: Returns to practice Thursday
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Sanders (appendix) was a limited practice participant Thursday.
Sanders underwent surgery to have his appendix removed on Tuesday, Sept. 22, and he didn't play in Week 3 against the Chargers. The second-year pro didn't practice Wednesday to begin Week 4 prep, but he was able to participate in a limited capacity Thursday. That's a good sign Sanders is healing well, though it remains to be seen if he'll be ready to suit up Sunday versus New England.
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Bills' C.J. Gardner-Johnson: Secures key interception in win
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Gardner-Johnson logged five tackles (three solo) and two passes defensed, including one interception, in the Bills' 24-16 win over the Chargers on Sunday.
Quarterback Justin Herbert threw Gardner-Johnson a "meatball sub", according to commentator Tom Brady, early in the fourth quarter of Sunday's game. The pick resulted in the Bills taking a lead for the first time in the game, with the 17-13 score becoming the closest gap in the remainder of the contest. The safety intercepted the ball at the 1-yard line, likely saving a touchdown or, at the very least, a field goal. Gardner-Johnson played 68 of the team's 69 defensive plays in the contest.
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Bills' Greg Rousseau: Logs third consecutive two-sack performance
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Rousseau logged eight tackles (five solo), including 2.0 sacks, in the Bills' 24-16 win over the Chargers on Sunday.
Rousseau leads the NFL with 6.0 sacks, having logged 2.0 sacks in each of the first three games of the 2026 regular season. The linebacker has had a stunning breakout since switching to coach Jim Leonhard's 3-4 defense. The 26-year-old is entering his sixth NFL season and has begun to make a compelling case that should put him on Defensive Player of the Year ballots if he can keep producing throughout the season.
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Phidarian Mathis: No longer with Buffalo
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The Bills released Mathis on Tuesday, Sal Capaccio of WGR Sports Radio 550 Buffalo reports.
Mathis was reinstated to the Bills' active roster Monday after serving his three-game suspension, but the 2022 second-rounder will not be a member of the team's 53-man roster moving forward. He could remain in Buffalo on the practice squad, but Mathis will have the opportunity to explore his options and should garner interest from teams looking to add depth to the defensive line.
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Bills' Christian Benford: Won't return Sunday
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Benford (toe) has been ruled out for the rest of Sunday's game against the Chargers.
Benford left the game in the third quarter due to a toe injury, which is severe enough for him to be sidelined for the rest of Sunday's contest. Te'Cory Couch and Davison Igbinosun will continue to operate in elevated roles in Benford's absence.
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Bills' Christian Benford: Exits game with toe injury
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Benford (toe) is questionable to return to Sunday's game against the Chargers.
Benford went to the locker room after sustaining a toe injury in the third quarter, and he'll be evaluated by trainers to determine whether he can return to Sunday's contest. Davison Igbinosun and Te'Cory Couch are in line for more defensive snaps for as long as Benford is out of the game.
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Bills' Ed Oliver: Returning to action in Week 3
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Oliver (hip) is available for Sunday's game versus the Chargers.
Oliver didn't play in the Week 2 win over Detroit due to a hip injury. However, despite carrying a questionable tag for the Week 3 meeting with the Chargers, the veteran will be back on the field, likely resulting in less work for DeWayne Carter.
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Bills' Jordan Hancock: Placed on injured reserve
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The Bills placed Hancock (hamstring) on injured reserve Friday.
Hancock likely suffered his hamstring injury in the Bills' Week 2 win over the Lions. The issue appears to be significant, leading the team to move Hancock to IR. The defensive back will need to miss at least four games before becoming eligible to return to the Bills' active roster. The team signed Greg Dortch from the practice squad to the active roster in a corresponding move.
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Bills' T.J. Sanders: Ruled out Sunday
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Sanders (Appendix) won't play in Sunday's game against the Chargers.
Sanders underwent an appendectomy Tuesday, so it's unknown how long he will be off the field. With Ed Oliver (hip) questionable, Landon Jackson may be busier than usual.
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Bills' Ed Oliver: Questionable against Chargers
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Oliver (hip) is listed as questionable for Sunday's game against the Chargers.
Oliver injured his hip during warmups ahead of the Week 2 win over the Lions. He didn't practice Wednesday. However, the veteran practiced in a limited capacity Thursday and Friday, so despite the questionable designation, it appears he at least has a shot to play. If Oliver can't suit up versus Los Angeles, DeWayne Carter should be in line for more work once again.
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Bills' Ed Oliver: Limited at practice Thursday
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Oliver (hip) was limited during Thursday's practice.
Oliver suffered a hip injury during warmups ahead of the 41-31 win over Detroit in Week 2. The veteran didn't practice Wednesday. However, since he was back in a limited capacity Thursday, it appears he's trending favorably toward returning for the Week 3 meeting with the Chargers. If Oliver ends up missing a second consecutive game, DeWayne Carter may continue to see more snaps.
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Bills' T.J. Sanders: DNP Wednesday
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Sanders (appendix) did not participate in Wednesday's practice, Katherine Fitzgerald of The Buffalo News reports.
Sanders did not play in the Bills' Week 2 win over the Lions due to a knee injury and an illness. The defensive tackle's absence during the first practice of Week 3 came for a different reason, as Sanders' appendix was surgically removed Tuesday. It remains unclear how long it will take the 23-year-old to return to football shape.
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Bills' Christian Benford: Leads team in tackles
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Benford logged eight tackles (five solo) and two passes defensed during the Bills' 41-31 win over the Lions on Thursday night.
Benford led the Bills in tackles on the night, with linebacker Dorian Williams coming in second with six. Benford did yield a touchdown to Amon-Ra St. Brown at the start of the third quarter despite sticking tight to the wide receiver on a quick slant route. The team's primary outside cornerback played 64 out of the 65 defensive snaps over the course of the night.
