Reed (ribs) is listed as questionable ahead of Sunday's game against the Panthers.
Reed logged limited practice sessions throughout the Lions' Week 4 preparations. The cornerback's status for Sunday's contest remains uncertain as he works through the rib issue he suffered in the Week 3 win over the Jets. If Reed cannot suit up, Rock Ya-Sin will likely start at outside cornerback across from Ennis Rakestraw.
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Lions' Brian Branch: Nearing return from torn Achilles
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Head coach Dan Campbell said Friday that Branch (Achilles) is close to returning, Tim Twentyman of the Lions' official site reports.
"Close" is a relative term, so it's unclear how close Branch actually is, considering he remains on the reserve/PUP list and has yet to begin practicing. It sounds like that could change next week. The Lions have been relying on Roger McCreary at slot cornerback in Branch's absence.
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Lions' D.J. Reed: Working through rib injury
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Reed (ribs) was a limited participant in Wednesday's practice.
Reed presumably picked up the injury during the Lions' 31-24 win over the Jets in Week 3, when he played 62 of 66 defensive snaps (93.9 percent) and finished with eight tackles (five solo) and one pass defense. He'll have two more chances to increase his practice participation to full and avoid an injury designation for Sunday's road game against the Panthers.
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Lions' Derrick Barnes: Notches eight stops in Week 3
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Barnes registered eight tackles (five solo) and a defensed pass Sunday in a 31-24 victory against the Jets.
Barnes tied with D.J. Reed for the second-most tackles on Detroit behind Christian Izien (11). Barnes has been consistent to begin the campaign, recording between six and eight stops in each of his three games so far. He also has 2.0 sacks on the campaign, halfway to his career-high total over 17 regular-season contests last year.
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Lions' Chuck Clark: Posts another strong performance in Week 3
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Clark finished Sunday's 31-24 win over the Jets with seven tackles, including 1.0 sacks, and a forced fumble.
Clark continues to start at safety for Detroit with with Brian Branch (Achilles) and Kerby Joseph (knee) both on the PUP list. Clark logged just a 45 percent defensive snap share in Week 1, but he upped that to 86 percent in Week 2 before playing every one of the Lions' 61 defensive snaps in Week 3. The veteran defender came up with a huge play late in the contest, sacking Jets QB Geno Smith and causing him to fumble with less than a minute remaining and New York nearing the red zone while trailing by seven points. The sack was Clark's first since he played for the Jets in 2024.
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Lions' Christian Izien: Racks up 11 stops in Week 3
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Izien posted 11 tackles (nine solo) and one defensed pass Sunday in a 31-24 win over the Jets.
Izien paced the Lions in stops while playing all but two of the team's defensive snaps. The 26-year-old appears to be fully recovered from the groin injury that caused him to sit out Detroit's season opener. Izien has taken on a starting safety role due to Brian Branch (Achilles) and Kerby Joseph (knee) both being on the PUP list.
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Lions' Thomas Harper: Placed on injured reserve
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The Lions placed Harper (ankle) on injured reserve Saturday.
Harper has not been able to practice since sustaining an ankle injury during the Lions' Week 2 loss to the Bills. The safety departing for IR leaves the Lions' secondary dangerously low on defensive backs, now without Harper, Avonte Maddox (foot), Brian Branch (Achilles) and Kerby Joseph (knee). The Lions have elevated Jalen Mills from the practice squad to start at Strong Safety in Sunday's game against the Jets.
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Lions' Thomas Harper: Won't play in Week 3
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Harper (ankle) has been ruled out for Sunday's game against the Jets, Tim Twentyman of the Lions' official site reports.
Harper was held out of practice all week due to an ankle injury, which he likely picked up during the Lions' 41-31 loss to the Bills in Week 2. The Lions' secondary is thin, especially with Avonte Maddox (foot, IR) out for the rest of the 2026 season, meaning that Detroit will have to turn to options like Bishop Fitzgerald, Christian Izien and even Roger McCreary to start at safety next to Chuck Clark. Harper will aim to recover enough to return for Week 4 against the Panthers on Sunday, Oct. 4.
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Lions' Thomas Harper: Misses another practice Thursday
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Harper (ankle) did not practice Thursday, Nolan Bianchi of The Detroit News reports.
This will mark the second consecutive practice Harper has missed this week, so things aren't looking too promising ahead of the Week 3 meeting with the Jets. The 25-year-old appeared in both of Detroit's games this season, amassing five total tackles and two passes defended.
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Lions' Avonte Maddox: Officially moved to IR
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The Lions placed Maddox (foot) on injured reserve Tuesday.
Maddox will miss the rest of the 2026 season due to a left foot injury he sustained in the Lions' Week 2 loss to the Bills. He'll shift his focus toward being fully healthy for the 2027 campaign, though he'll enter the offseason as an unrestricted free agent. With Maddox, Brian Branch (Achilles) and Kerby Joseph (knee) all sidelined, Thomas Harper and Chuck Clark will serve as Detroit's starting safeties for the time being.
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Lions' Avonte Maddox: Done for 2026
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Maddox will undergo season-ending surgery for a left foot injury that he sustained during the Lions' 41-31 loss to the Bills on Thursday, Dave Birkett of the Detroit Free Press reports.
Maddox was spotted wearing a boot on his left foot following Thursday's loss, and after undergoing multiple tests and imaging, season-ending surgery has been determined as the best course of action for the veteran defensive back. With both Kerby Joseph (knee) and Brian Branch (Achilles) on the reserve/PUP list and Maddox done for the year, the Lions will turn to Chuck Clark and Thomas Harper to be the starting safeties for the time being.
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Lions' Aidan Hutchinson: Notches sack in loss
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Hutchinson logged three tackles (two solo), including 1.0 sacks, during the Lions' 41-31 loss to the Bills on Thursday night.
Hutchinson sacked Josh Allen on the third play of the game, forcing a fumble that right tackle Spencer Brown recovered. The Lions' top pass rusher almost notched another on the Bills' quarterback, but Allen was able to fend off the 6-foot-7, 268-pounder long enough to send the ball out of bounds. Hutchinson had a very top-heavy night, mostly fending off plays designed to get away from the defensive end as the Bills tried to run out the clock for the majority of the second half.
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Lions' Jack Campbell: Logs six tackles in loss
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Campbell made six tackles (two solo) in the Lions' 41-31 loss to the Bills on Thursday night.
Campbell played all 74 defensive snaps for the Lions, displaying intense physical conditioning against a Bills offense that was constantly on the field. The starting middle linebacker posted a similar stat line during Week 1 in a long game against the Saints, showing consistent availability and production for the team's defense.
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Lions' Derrick Barnes: Picks up sack in loss
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Barnes recorded seven tackles (five solo), including 1.0 sacks, in Thursday's 41-31 loss to the Bills.
The linebacker also had a big day in Week 1, finishing with six tackles (three solo), including 1.0 sacks, and two pass breakups, including an interception. He's off to a strong start to the season despite Detroit's defensive struggles.
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Lions' Chuck Clark: Makes 11 tackles in defeat
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Clark finished with 11 tackles (four solo) in Thursday's 41-31 loss to the Bills.
The safety was active on a night when the Lions had trouble stopping the Bills. Clark remains in a starting spot for now with Kerby Joseph (knee) on the reserve/PUP list to begin the season.
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Lions' Avonte Maddox: On crutches, in a boot
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Maddox left the locker room on crutches and wearing a boot on his injured left foot after Thursday night's loss to the Bills, Justin Rogers of DetroitFootball.net reports.
It's not looking good for the safety/cornerback, who had to leave Thursday's 41-31 loss to the Bills during the first half. Maddox had started the first two games at strong safety for Detroit with Brian Branch (Achilles) beginning the season on the reserve/PUP list. It appears now that the Lions may have to turn to Thomas Harper to man the position.
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Lions' Avonte Maddox: Done for the game
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Maddox (foot) has been ruled out for the rest of Thursday's matchup with the Bills, Eric Woodyard of ESPN.com reports.
The safety exited in the first half after making three tackles (one solo). Thomas Harper is the next man up at safety for the Lions.
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Lions' D.J. Reed: Active against Bills
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Reed (foot) is active for Thursday's game against the Bills.
Reed has been battling a foot injury, but he will have the green light to suit up versus Buffalo after carrying a questionable tag heading into the contest. The 29-year-old was heavily involved in the 31-30 overtime win over the Saints in Week 1, amassing 10 total tackles and one pass defended.
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Lions' D.J. Reed: Questionable versus Buffalo
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Reed (foot) is listed as questionable for Thursday's game against Buffalo.
Reed is dealing with a foot injury, so the questionable tag isn't much of a surprise. If Reed can't get on the field versus the Bills, Roger McCreary or Keith Abney could see more action opposite Rock Ya-Sin.
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Lions' Jack Campbell: Tallies seven tackles vs. New Orleans
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Campbell posted seven tackles (five solo) during the Lions' 31-30 overtime win over the Saints on Sunday.
Campbell was the only Lions player to play all 90 defensive snaps during Sunday's OT win, and he finished tied for the second-most tackles on the team behind D.J. Reed (10, foot). Campbell entered 2026 on the heels of a career year in 2025, when he tallied 176 tackles (89 solo), including 5.0 sacks, four pass defenses, three forced fumbles and two fumble recoveries across 17 regular-season games. The fourth-year linebacker inked a four-year, $81 million contract extension with the Lions in May, ensuring that the Iowa product will be a key piece to defense for years to come.