Greenlaw (quadriceps) did not practice Thursday, Nick Wagoner of ESPN.com reports.
Greenlaw suffered a quadriceps injury late in the victory over Arizona on Sunday. Since then, he has missed two consecutive practices, so he will have another opportunity Friday to make some progress. If Greenlaw is unavailable versus Denver in Week 4, Garret Wallow may be needed to fill the void in the lineup.
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49ers' Gracen Halton: Fades injury report
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Halton (ankle) was not listed on Wednesday's practice report, Vic Tafur of The Athletic reports.
Halton did not return to the 49ers' Week 3 win over the Cardinals due to an ankle injury. However, his absence from Wednesday's injury report indicates that his ankle is fine, and the rookie fourth-rounder should be available for Sunday's home game against the Broncos. Halton has eight tackles (five solo) and one pass defense through the first three games of the regular season.
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49ers' Dre Greenlaw: DNP to open Week 4 prep
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Greenlaw (quadriceps) didn't practice Wednesday, Vic Tafur of The Athletic reports.
Greenlaw injured his quad during the fourth quarter of the 49ers' 36-30 win over the Cardinals in Week 3, when he logged eight tackles (three solo). The veteran linebacker will need to return to practice in at least a limited capacity over the coming days to have a realistic chance of playing against the Broncos on Sunday. If Greenlaw is unable to play, then Garret Wallow would likely start alongside Fred Warner and Jaden Dugger at linebacker.
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49ers' Mykel Williams: Opens practice window
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The 49ers opened Williams' (knee) 21-day practice window Wednesday to return from the reserve/PUP list, Matt Maiocco of NBC Sports Bay Area reports.
Williams spent his first practice back with the 49ers as a limited participant. The team has until Oct. 21. to add the linebacker to the 53-man roster, or he will remain on the reserve/PUP list for the remainder of the 2026 season. Williams is still recovering from a torn ACL he suffered in November 2025 but could suit up for game day as soon as Week 5.
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49ers' Renardo Green: Records 13 tackles in Week 3
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Green recorded 13 tackles (seven solo) and one pass breakup in Sunday's 36-30 win over the Cardinals.
With the Cardinals running 87 offensive plays, it led to inflated tackle numbers across the board for the San Francisco defenders, and it was Green's second career game with double-digit tackles. Through three games this season, Green has 18 tackles (10 solo) and two pass breakups, including one interception.
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49ers' Fred Warner: Piles up 17 tackles in Week 3 win
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Warner recorded 17 tackles (eight solo) in Sunday's win over Arizona.
The Cardinals ran a whopping 87 offensive plays Sunday, and Warner was on the field for all of them, leading to the inflated tackles number. The 17 tackles were the most Warner has ever recorded in a single game during his nine-year career. Through three games this season, Warner has 33 tackles (14 solo), including 0.5 sacks, two forced fumbles and one pass breakup.
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Tracy Walker: Suspension lifted after Week 3
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Walker has been reinstated after serving a three-game suspension, Aaron Wilson of KPRC 2 Houston reports.
Walker is no stranger to NFL suspensions, having served a 12-game suspension last year. The safety is now cleared to suit up for any game with any franchise, but the 31-year-old remains a free agent looking for work.
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Xavier Thomas: Ready for action after suspension
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Thomas has been reinstated after serving a three-game suspension, Aaron Wilson of KPRC 2 Houston reports.
The 49ers waived Thomas from IR with an injury settlement in late August. Since then, the linebacker has been patiently awaiting reinstatement by the NFL. Thomas is free to join any team or practice squad and can now fully commit to any game-day action.
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Victor Dimukeje: Tries out with New England
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Dimukeje (undisclosed) worked out for the Patriots on Tuesday, Mike Reiss of ESPN.com reports.
Dimukeje spent part of training camp with San Francisco but landed on IR due to an undisclosed issue in late August. He was eventually released with an injury settlement, and the 26-year-old now appears to be healthy. Dimukeje had a somewhat promising 2023 campaign with Arizona, when he logged 4.0 sacks over 16 regular-season contests, but those remain his only sacks across his five-year NFL career.
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49ers' James Thompson: Won't play Week 4
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Thompson (ankle) won't play in San Francisco's Week 4 matchup versus the Broncos, Jennifer Lee Chan of NBC Sports Bay Area reports.
Thompson is in line to miss a second consecutive game due to the high-ankle sprain he suffered during the Week 2 win over the Dolphins. While there's currently no timetable for his return, his next chance to play will be the Week 6 matchup against Seattle.
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49ers' Nick Bosa: Ruled out for Week 4
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Coach Kyle Shanahan said Monday that Bosa (calf) won't play this coming Sunday against the Broncos, Cam Inman of The San Jose Mercury News reports.
After Bosa strained his calf at practice last Thursday, Shanahan told Matt Barrows of The Athletic that the pass rusher would miss "a few weeks," so a second consecutive absence in Week 4 comes as no surprise. The 49ers started Ogbo Okoronkwo and Keion White at defensive end during Sunday's win versus the Cardinals and likely will continue to lean on the duo until Bosa is able to return to action.
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49ers' Dre Greenlaw: Nursing quad injury
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Greenlaw (quadriceps) is questionable to return to Sunday's game against the Cardinals, Eric Branch of the San Francisco Chronicle reports.
Greenlaw sustained the injury early in the fourth quarter, and he's been off the field being monitored by training staff since his exit. Garrett Wallow is in the game at weakside linebacker in Greenlaw's absence.
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49ers' Renardo Green: Clears concussion check
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Green (head) has returned to Sunday's game against the 49ers, Eric Branch of the San Francisco Chronicle reports.
Green was being evaluated by medical staff for a possible concussion after taking a hit to the head. He has been cleared by trainers to return and is back on the field for the fourth quarter.
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49ers' Gracen Halton: Exits game with ankle injury
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Halton (ankle) is questionable to return to Sunday's game against Arizona, Jennifer Lee Chan of NBC Sports Bay Area reports.
Halton had to be helped off the field by trainers after sustaining an ankle injury, and he's been taken to the locker room for further evaluation. Naquan Jones, Kevin Givens and Sebastian Valdez are all in line for more defensive snaps for as long as Halton is out of the game.
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49ers' Jack Jones: Cleared for Week 3
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Jones (foot) is active for Sunday's game against the Cardinals, Brooke Evans of the 49ers' official site reports.
Jones sustained a foot injury in the 49ers' Week 2 win over the Dolphins, but the fifth-year pro has been cleared to play in Sunday's NFC West showdown. He's logged three pass defenses and zero tackles through the first two games of the regular season while serving in a rotational role in the secondary.
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49ers' James Thompson: Sidelined versus Arizona
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Thompson (ankle) is listed as out for Sunday's game against Arizona.
Thompson suffered a high-ankle sprain in the 35-13 victory over the Dolphins in Week 2. While nothing has been made official, an injury of this nature likely means he will miss more time moving ahead. The rookie appeared in both of the 49ers' games to begin the 2026 campaign, amassing four total tackles (one solo).
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49ers' Nick Bosa: Won't play Sunday
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Bosa (calf) has been ruled out ahead of Sunday's game against the Cardinals.
Coach Kyle Shanahan said that Bosa is expected to miss "a few weeks" with a calf issue, Matt Barrows of The Athletic reports. It is unclear if Bosa will need to miss the minimum of four games that placement on IR would require. Even if he must miss more than four games, the team may not place the 28-year-old on IR anyway because it has almost reached its limit of eight designated-to-return players.
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49ers' Nick Bosa: Injures calf, likely out multiple weeks
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Bosa injured his calf during Thursday's practice and is expected to miss "a few weeks," according to Adam Schefter of ESPN.
Schefter reports that the 49ers aren't yet sure if Bosa will go on injured reserve. Either way, he's apparently set to miss multiple games, leaving a top-heavy roster without one of its superstars.
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49ers' Romello Height: Doesn't practice Thursday
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Height (hand) did not participate in Thursday's practice, Jennifer Lee Chan of NBC Sports Bay Area reports.
Height has missed each of the first two practices of Week 3 prep after undergoing hand surgery Tuesday. His status for Sunday's game against the Cardinals will become more clear once the 49ers release their injury designations following Friday's practice. Nick Bosa (calf/knee) is also working through lower-body injuries, leaving Keion White, Khalid Kareem and Ogbo Okoronkwo currently as the only healthy pass rushers on the 49ers' active roster.
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49ers' Nick Bosa: DNP with lower-body injuries
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Bosa (calf/knee) did not participate in Thursday's practice, Jennifer Lee Chan of NBC Sports Bay Area reports.
It's the second day in a row in which Bosa has been held out of practice due to knee and calf injuries. His practice participation Friday will provide more clarity on his status ahead of Sunday's NFC West showdown against the Cardinals. Romello Height (hand) is also working through an injury, so Ogbo Okoronkwo and Khalid Kareem could operate in expanded roles against Arizona, depending on the statuses of both Bosa and Height.
