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The No. 12 Illinois Fighting Illini and the Indiana Hoosiers are set to square off in a Big Ten matchup at 9 p.m. ET on Tuesday at Assembly Hall. IU is 9-7 overall and 4-3 at home, while the Fighting Illini are 11-5 overall and 3-2 on the road. Both teams have a 10-6 mark against the spread this season. 

The Fighting Illini are favored by 2.5 points in the latest Indiana vs. Illinois odds from William Hill Sportsbook, and the over-under is set at 143. Before entering any Illinois vs. Indiana picks, you'll want to see the college basketball predictions from the model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of almost $2,300 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Indiana vs. Illinois. You can head to SportsLine to see its picks. Here are several college basketball odds for Illinois vs. Indiana:

  • Indiana vs. Illinois spread: Indiana +2.5
  • Indiana vs. Illinois over-under: 143 points

What you need to know about Indiana

Indiana fell 74-70 to the Rutgers Scarlet Knights in its last outing. Guard Armaan Franklin (14 points) and forward Trayce Jackson-Davis (13 points) were the top scorers for IU. Finding consistency has been the challenge for Indiana this season. The Hoosiers showed tremendous upside in a win over then-No. 4 Iowa on Jan. 21. But overall, Indiana hasn't won more than two straight games at any point this season and sits at 4-5 in Big Ten play. 

Jackson-Davis leads the team with 20.1 points and 8.7 rebounds. Franklin averages 12.8 ppg and is hitting 45.5 percent of his 3-point attempts. The Hoosiers only give up 68.1 points per game, but they haven't been consistent enough offensively to capitalize on that on a regular basis, ranking 166th nationally with 72.9 points per game.

What you need to know about Illinois

Illinois beat the then-No. 7 Iowa Hawkeyes 80-75 this past Friday. Illinois' success was spearheaded by the efforts of guard Trent Frazier, who had 24 points, and guard Ayo Dosunmu, who had 25 points. Illinois is second in the Big Ten standings, tied with Ohio State at 1.5 games behind Michigan. 

Dosunmu leads the way with 21.9 points and 4.8 assists per contest. Center Kofi Cockburn is one of the nation's best post players and he averages 16.9 points, 10.3 rebounds and 1.4 block per game. Illinois knocked off Indiana 69-60 on Dec. 26, covering the 6.5-point spread. 

How to make Indiana vs. Illinois picks

The model has simulated Indiana vs. Illinois 10,000 times and the results are in. It is leaning over on the total, and it's also generated a point-spread pick that is hitting in well over 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Indiana vs. Illinois? And which side of the spread is hitting in well over 60 percent of simulations? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.