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A Big East battle is on tap between the Creighton Bluejays and the Seton Hall Pirates at 7 p.m. ET on Friday at the Prudential Center. Seton Hall is 14-7 overall and 4-6 in Big East play, while Creighton is 13-7 overall and 5-4 in the conference. The Bluejays have won and covered the spread in the last four head-to-head meetings with their Big East rivals.

And it's been Creighton who has been the better team against the spread of late, covering six of nine, while Seton Hall has gone 1-5-1 against the number its last seven games. Still, the Pirates are favored by six points at home in the latest Seton Hall vs. Creighton odds and the over-under is set at 135.5. Before making any Creighton vs. Seton Hall picks, you'll want to see the college basketball predictions from the model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $2,400 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Seton Hall vs. Creighton. You can head to SportsLine to see its picks. Here are several college basketball odds for Creighton vs. Seton Hall:

  • Seton Hall vs. Creighton spread: Seton Hall -6
  • Seton Hall vs. Creighton over-under: 135.5 points

What you need to know about Seton Hall

The Pirates are coming off a 70-63 win over Georgetown on Tuesday where they got a big performance from third-year forward Tray Jackson. The Missouri transfer now in his second season with Seton Hall went 5-for-9 from the 3-point line on his way to 21 points in the victory.

The team's leading scorer, Jared Rhoden (15.5 ppg), also had 14 points and six rebounds in the win. Seton Hall was missing sixth-year guard Bryce Aiken for the fourth straight game against Georgetown as he remains in concussion protocol, but the former Harvard star does have a chance to return on Friday night. He's averaging 14.5 points per game this season.

What you need to know about Creighton

Creighton also played on Tuesday night, grinding out a 59-55 win over Connecticut to get back over .500 in Big East play. Ryan Hawkins had a huge game with 23 points on 8-for-12 shooting (4-for-5 from the 3-point line) and also added 11 rebounds for his sixth double-double of the season.

Hawkins is averaging 13.1 points and 7.5 rebounds per game after transferring in from Division II Northwest Missouri State, where he scored 2,098 points in his career. Hawkins combines with Ryan Kalkbrenner and Arthur Kaluma go give Creighton one of the best frontcourts in the conference and it will be leaning on that bulk up front on Friday.

How to make Creighton vs. Seton Hall picks

The model is leaning over on the total and it's also generated a point-spread pick that is hitting in well over 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Seton Hall vs. Creighton? And which side of the spread hits well over 60 percent of the time? Visit SportsLine now to find out, all from the model that has crushed its college basketball picks.