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The No. 20 UCLA Bruins and the Arizona State Sun Devils are set to square off in a Pac-12 matchup at 10:30 p.m. ET on Saturday, October 2 at the Rose Bowl in Pasadena, Calif. The Bruins are 3-1 overall and 2-1 at home, while ASU is 3-1 overall and 0-1 on the road. Both teams won their conference openers last weekend.

UCLA is favored by 3 points in the latest UCLA vs. Arizona State odds from Caesars Sportsbook, and the over-under is set at 55. Before entering any Arizona State vs. UCLA picks, you need to check out the college football predictions from the proven computer simulation model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,300 for $100 players on its top-rated college football picks against the spread. After going a sizzling 9-3 in Week 4, It also enters Week 5 of the 2021 season on an 81-61 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on UCLA vs. Arizona State and just released its CFB picks and predictions. You can head to SportsLine to see the model's picks. Here are several college football odds and betting lines for UCLA vs. Arizona State:

  • UCLA vs. Arizona State spread: UCLA -3
  • UCLA vs. Arizona State over-under: 55 points
  • UCLA vs. Arizona State moneyline: UCLA -170, ASU +145

What you need to know about UCLA

UCLA bounced back from their loss to Fresno State, beating the Stanford Cardinal 35-24 last Saturday. UCLA quarterback Dorian Thompson-Robinson was outstanding, throwing for 252 yards and two touchdowns, and rushing for 31 yards and another two scores. Near the top of the highlight reel was Thompson-Robinson's 75-yard TD bomb to WR Kyle Philips in the fourth quarter.

While UCLA's offense is explosive and balanced, its defense has been stellar against the run (64 yards per game allowed) and below average against the pass (330.3 yards allowed per game). This could bode well for the Bruins, as Arizona State's rushing attack has been the strength of its offense in 2021.

What you need to know about Arizona State

ASU made easy work of the Colorado Buffaloes on Saturday, rattling off a 35-13 win. ASU quarterback Jayden Daniels was dynamic, accounting for he 236 passing yards in addition to rushing for two TDs and 75 yards.

Arizona State owns a clear advantage on the defensive side of the ball in this matchup, allowing only 247.5 yards and 16 points per game. The matchup between ASU's defense and UCLA's offense could ultimately be the deciding factor in this critical Pac-12 game.

How to make Arizona State vs. UCLA picks

The model has simulated UCLA vs. Arizona State 10,000 times and the results are in. We can tell you that the model is leaning under on the point total, and it's also generated a point-spread pick that is hitting in over 60 percent of simulations. You can only see the model's UCLA vs. Arizona State ATS pick at SportsLine.

So who wins UCLA vs. Arizona State? And which side is covering more than 60 percent of the time? Visit SportsLine now to see which side of the Arizona State vs. UCLA spread to jump on, all from the advanced model that is on an 81-61 run on top-rated picks, and find out.