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Both teams are trying to start a strong stretch run on Friday night when the Virginia Tech Hokies and Boston College Eagles face off in an ACC matchup at BC Alumni Stadium. The Hokies (4-4, 2-2 Atlantic Coast) have a minuscule shot at challenging Pittsburgh for the Coastal Division crown, while the Eagles (4-4, 0-4) are at the bottom of the Atlantic Division. Virginia Tech beat Georgia Tech 26-17 last Saturday to halt a three-game losing skid that included a loss to Coastal leader Pitt, which is 3-1 in the ACC. BC lost 21-6 to Syracuse last weekend, its fourth loss in a row. The teams both take the same approach, relying on strong defense and running the ball.

Kickoff is set for 7:30 p.m. ET in Chestnut Hill, Mass. The Hokies are 2.5-point favorites in the latest Virginia Tech vs. Boston College odds from Caesars Sportsbook, and the over-under for total points is set at 50. Before making any Boston College vs. Virginia Tech picks or bets, make sure you check out the college football predictions and betting advice from the red-hot SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,700 for $100 players on its top-rated college football picks against the spread. It also enters Week 10 of the 2021 season on a 28-15 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, the model has locked in on Virginia Tech vs. Boston College and just released its coveted CFB picks and predictions. You can head to SportsLine now to see all of the model's picks. Now, here are the college football Week 10 odds and betting lines for Boston College vs. Virginia Tech:  

  • Virginia Tech vs. Boston College spread: Hokies -2.5
  • Virginia Tech vs. Boston College over-under: 50 points 
  • Virginia Tech vs. Boston College money line: Hokies -135, Eagles +115
  • VT: It is 5-12 ATS as a road favorite since 2016 
  • BC: It is 8-6-1 ATS as a home underdog since 2016

Why the Hokies can cover

Virginia Tech is 11-11 against the spread in conference games since 2019, and it has won nine of the past 13 matchups. That includes a 40-14 rout last season in Blacksburg. The Hokies should have little trouble moving the ball on the ground against an Eagles defense that yields 173 rushing yards per game (90th in FBS). The Hokies rank just 73rd (160.6), but Raheem Blackshear averaged 5.9 yards per carry in last week's win, and Malachi Thomas rushed for 103 yards. The two running backs have combined for 660 yards and seven TDs this season.

Quarterback Braxton Burmeister has 1,485 passing yards, with nine TDs and just three interceptions, and he has added 228 yards to the rushing effort. Receiver Tre Turner (602 yards, 17.7 per catch) is a major threat, and Tayvion Robinson (31 catches) is an excellent safety valve. The Tech defense is led by linebackers Alan Tisdale (team-high 65 tackles) and Dax Hollifield (3.5 sacks, one interception) and allows just 22.4 points per game. It has 19 sacks, and Jermaine Waller has picked off four passes. The Eagles have turned the ball over 12 times.

Why the Eagles can cover

The home team is 4-1 ATS in the last five meetings, and BC averaged more than 41 points per game in their first four but is at just 25 during its slide. Quarterback Dennis Grosel has had a rough patch, but he completed 68.5 percent of his throws, with six TDs and three picks, in limited action last season. He has the weapons in Zay Flowers (511 yards, 14.6 per catch) and tight end Trae Berry (288, 16 per reception) to get him out of the funk, but running back Pat Garwo III can carry the load in the meantime. The sophomore has 689 yards and five TDs and has topped 150 yards twice.

Garwo averages 5.9 yards per carry and will be facing a Hokies defense that allows 178 rushing yards per game (95th in FBS). The BC defense ranks 33rd in the nation in allowing 20.8 points per contest, and it is 11th against the pass (174 yards per game). The Hokies passing attack is 103rd, so BC can focus on stopping their 73rd-ranked rushing attack. Brandon Sebastian (three interceptions) and Josh DeBerry (two) lead a secondary that has helped produce 12 takeaways, and Khris Banks and Marcus Valdez will harass Burmeister, who has been sacked 19 times.

How to make Virginia Tech vs. Boston College picks

The model is going over on the total, projecting the teams to combine for 53 points. It has also generated a point-spread pick that is hitting in well over 50 percent of simulations. You can only get the model's Boston College vs. Virginia Tech pick at SportsLine. 

So who wins the Boston College vs. Virginia Tech matchup on Friday night? And which side of the spread is hitting well over 50 percent of the time? Visit SportsLine right now to see which side of the Virginia Tech vs. Boston College spread to back Friday, all from the advanced model on a 28-15 run on its top-rated college football picks, and find out.