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The Arizona Cardinals will take on the Philadelphia Eagles at 4:05 p.m. ET on Sunday at State Farm Stadium. Arizona is 7-6 overall and 3-3 at home, while Philadelphia is 4-8-1 overall and 1-5 on the road. The Eagles snapped a four-game losing streak with a win last week. The Cardinals halted a three-game losing streak with their Week 14 win. 

Arizona is favored by 6.5 points in the latest Cardinals vs. Eagles odds from William Hill Sportsbook, and the over-under is set at 49.5. Before entering any Eagles vs. Cardinals picks, you'll want to see the NFL predictions from the model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up almost $7,900 for $100 players on top-rated NFL picks since its inception five-plus years ago. It is a sizzling 22-11 on top-rated NFL picks this season, returning over $800. The model also enters Week 15 on an incredible 118-76 run on top-rated NFL picks that dates back to the 2017 season.

The model ranked in the Top 10 on NFLPickWatch three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Cardinals vs. Eagles. You can head to SportsLine to see its picks. Here are several NFL betting lines for Eagles vs. Cardinals:

  • Cardinals vs. Eagles spread: Cardinals -6.5
  • Cardinals vs. Eagles over-under: 49.5 points
  • Cardinals vs. Eagles money line: Philadelphia +235, Arizona -275

What you need to know about the Cardinals

The Cardinals rolled past the New York Giants this past Sunday, 26-7. Haason Reddick had career highs in sacks (five) and forced fumbles (three). He became the first player with five sacks and three fumbles in a single game since 2002. Dan Arnold has four TD receptions in his past four games and is aiming for his third game in a row with a TD catch. 

DeAndre Hopkins had nine receptions for 136 yards last week. He has six games with 100-plus yards in 2020, tied for the most in the NFL. Hopkins ranks 3rd in receptions (94) and fifth in receiving yards (1,155) this season. He is the seventh player in NFL history with four consecutive seasons with 90-plus catches and 1,100-plus yards.  

Kenyan Drake had 90 scrimmage yards (80 rushing) and a rushing TD last week. He has a rushing TD in four consecutive games. Drake needs 49 scrimmage yards for his third consecutive season with 1,000-plus scrimmage yards.  

What you need to know about the Eagles

Meanwhile, the Eagles scored a 24-21 win over the New Orleans Saints this past Sunday. Miles Sanders rushed for two TDs and 115 yards on 14 carries, including a 82-yard touchdown run. He is the only player in the NFL with three runs of 60-plus yards this season. Sanders has 75-plus scrimmage yards in four of his past five games on the road. He is one of three running backs with five-plus yards per carry (5.0) since 2019 (minimum 300 attempts). 

Jalen Hurts made his first NFL start in Week 14. He passed for 167 yards and a TD vs. zero INTs for an 83.6 rating  and had 106 rushing yards. He joined Lamar Jackson (2018) as the only quarterbacks with 100-plus rushing yards in their first career starts. Fletcher Cox has a sack in five of his past six games. He has 6.5 sacks in 2020, his sixth career season with five-plus sacks.

How to make Cardinals vs. Eagles picks

The model has simulated Cardinals vs. Eagles 10,000 times and the results are in. It is leaning under on the total, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Cardinals vs. Eagles? And which side of the spread hits in over 50 percent of simulations? Visit SportsLine now to see which side of the Eagles vs. Cardinals spread to jump on Sunday, all from the model that enters Week 15 of the NFL season on an incredible 118-76 roll.