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The Carolina Panthers and the Atlanta Falcons are set to square off in an NFC South matchup at 1 p.m. ET on Sunday at Bank of America Stadium. The Panthers are 5-7 overall and 2-4 at home, while Atlanta is 5-7 overall and 4-2 on the road. The Panthers have lost three of their last four games. The Falcons have lost four of their last six. 

The Panthers won the first meeting of the season on Oct. 31, 19-13. Carolina is favored by 2.5 points in the latest Panthers vs. Falcons odds from Caesars Sportsbook, and the over-under is set at 41.5. Before entering any Falcons vs. Panthers picks, you'll want to see the NFL predictions from the model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up almost $7,200 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 14 of the 2021 season on an incredible 132-94 run on top-rated NFL picks that dates back to the 2017 season. 

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Panthers vs. Falcons. You can head to SportsLine to see its picks. Here are several NFL betting lines for Falcons vs. Panthers:

  • Panthers vs. Falcons spread: Panthers -2.5
  • Panthers vs. Falcons over-under: 41.5 points

What you need to know about the Panthers

Carolina lost 33-10 against the Miami Dolphins two weeks ago. Carolina fired offensive coordinator Joe Brady last week and running backs coach Jeff Nixon will now call plays. Cam Newton has 10 consecutive losses as a starting quarterback for the Panthers. His last win for Carolina was on Nov. 4, 2018. 

Chuba Hubbard had 82 rushing yards and a TD in the Week 8 meeting with Atlanta. He has 50-plus scrimmage yards in each of his five starts this season. Trent Scott (health and safety protocols) and John Miller (ankle) are out for Sunday's game. 

What you need to know about the Falcons

Atlanta lost to the Tampa Bay Buccaneers this past Sunday, 30-17. The Falcons were shut out in the second half. Atlanta has an 0-10 record against Tom Brady. Matt Ryan passed for 297 yards and was sacked five times. 

Cordarrelle Patterson had 96 scrimmage yards (78 rushing) last week and reached 1,000 scrimmage yards (1,007) for the first time in his career. Richie Grant (ankle) is questionable for Sunday's game.

How to make Panthers vs. Falcons picks

The model is leaning over on the total, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Panthers vs. Falcons? And which side of the spread hits well over 50 percent of the time? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks.