Regular season
| Wk | Date | OPP | Time | TV | Venue | Buy Tickets |
|---|---|---|---|---|---|---|
| 1 | Sep 11, 2022 | vs |
FOX
| Nissan Stadium | ||
| 2 | Sep 19, 2022 | @ |
ESPN
| Highmark Stadium | ||
| 3 | Sep 25, 2022 | vs |
FOX
| Nissan Stadium | ||
| 4 | Oct 2, 2022 | @ |
FOX
| Lucas Oil Stadium | ||
| 5 | Oct 9, 2022 | @ | FedEx Field | |||
| 6 | — |
BYE
| — | — | — | — |
| 7 | Oct 23, 2022 | vs | Nissan Stadium | |||
| 8 | Oct 30, 2022 | @ | NRG Stadium | |||
| 9 | Nov 6, 2022 | @ |
NBC
| GEHA Field at Arrowhead Stadium | ||
| 10 | Nov 13, 2022 | vs | Nissan Stadium | |||
| 11 | Nov 17, 2022 | @ |
AMZN
| Lambeau Field | ||
| 12 | Nov 27, 2022 | vs | Nissan Stadium | |||
| 13 | Dec 4, 2022 | @ |
FOX
| Lincoln Financial Field | ||
| 14 | Dec 11, 2022 | vs | Nissan Stadium | |||
| 15 | Dec 18, 2022 | @ | SoFi Stadium | |||
| 16 | Dec 24, 2022 | vs | Nissan Stadium | |||
| 17 | Dec 29, 2022 | vs |
AMZN
| Nissan Stadium | ||
| 18 | Jan 8, 2023 | @ | — | TIAA Bank Field |
