Alabama vs. Ole Miss prediction, odds, line: 2022 Week 11 SEC on CBS picks, best bets from computer model
SportsLine's model just revealed its college football picks, predictions and best bets for Ole Miss Rebels vs. Alabama Crimson Tide

The No. 9 Alabama Crimson Tide aim to avoid losing back-to-back games for the first time since 2013 when they visit the 11th-ranked Ole Miss Rebels in an SEC showdown on Saturday. Alabama (7-2, 4-2 SEC) hadn't dropped consecutive road contests since 2013-14 until falling 32-21 in overtime at LSU last week. However, the Crimson Tide is 54-9-2 all-time vs. Ole Miss (8-1, 4-1), which is coming off a 31-28 triumph at Texas A&M on Oct. 29.
Kickoff at Vaught-Hemingway Stadium in Oxford, Miss. is set for 3:30 p.m. ET. The Crimson Tide are 11-point favorites in the latest Alabama vs. Ole Miss odds from Caesars Sportsbook, while the over/under for total points scored is 65. Saturday's game can be seen live on CBS and streamed live on Paramount+ with their must-have Premium plan.
Sign up now to get a 7-day free trial at Paramount+. A subscription also gives you access to other sports content including the UEFA Champions League and Europa League, NWSL, NFL on CBS and countless movies and shows. Get it all free for seven days when you sign up right here.
And before making any Ole Miss vs. Alabama picks, you need to see the college football predictions and betting advice from the SportsLine Projection Model.
The model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.
Now, the model has set its sights on Alabama vs. Ole Miss and just locked in its picks and CFB predictions. You can visit SportsLine now to see the model's picks. Here are the college football odds and betting lines for Ole Miss vs. Alabama:
- Alabama vs. Ole Miss spread: Crimson Tide -11
- Alabama vs. Ole Miss over/under: 65 points
- Alabama vs. Ole Miss money line: Crimson Tide -420, Rebels +320
- BAMA: The Crimson Tide are 3-7 against the spread in their last 10 games at Ole Miss
- MISS: The Rebels are 1-6 ATS in their last seven home contests
- Alabama vs. Ole Miss picks: See picks here
- Alabama vs. Ole Miss streaming: Paramount+
Why Alabama can cover
The Crimson Tide haven't lost to the Rebels since 2015, winning each of the last six meetings. Alabama has scored at least 42 points in each of those contests and is averaging 56.7 during the streak. This season, the team has produced no fewer than 20 points and has recorded at least 30 in seven of its nine contests.
Alabama also has racked up the yardage against Ole Miss during coach Nick Saban's tenure. The Crimson Tide have averaged 466.5 yards versus the Rebels since 2007, amassing at least 500 six times and more than 600 on three occasions -- including a 723-yard effort in 2020. They registered 451 yards in last year's 42-21 victory, with Bryce Young throwing for 241 and a pair of touchdowns.
Why Ole Miss can cover
The Rebels are one of the top rushing teams in the nation as they rank third with an average of 267.4 yards. The ground attack is led by Quinshon Judkins, who leads all freshmen in the country with 1,036 yards and 13 rushing touchdowns. His TD total is the fifth-most in program history and the most by a freshman in school history.
Jaxson Dart threw for only 140 yards against Texas A&M but had three touchdown passes for the third time in four contests. The sophomore quarterback also was a factor with his legs as he nearly produced his third 100-yard effort of the season, finishing with 95 yards on 17 rushes. Senior wideout Jonathan Mingo, who is fifth in the nation in yards per reception (22.1), has set career highs with 30 catches, 664 yards and four TDs.
How to make Alabama vs. Ole Miss picks
SportsLine's model is leaning Over the total, projecting the teams to combine for 67 points. It also says one side of the spread hits in over 50% of simulations. You can only get the model's pick at SportsLine.
So who wins Alabama vs. Ole Miss? And which side of the spread hits over 50% of the time? Visit SportsLine now to see which side of the Ole Miss vs. Alabama spread to back, all from the advanced model that is up almost $3,000 on its top-rated college football spread picks, and find out, and don't forget to stream on Paramount+.















