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The Stanford Cardinal open their final Pac-12 season with new coach Troy Taylor at the Hawaii Rainbow Warriors on Friday night. Stanford enters a new era off a 3-9 record in 2022, with long time coach David Shaw resigning in the offseason. Hawaii played at Vanderbilt in Week 0 and kept the game close, losing 35-28 despite a furious fourth quarter rally. This is the teams' first matchup since 1972 with the Cardinal leading the series 3-0. Their most notable matchup with a 74-20 Stanford victory in the 1950 Pineapple Bowl.

Kickoff from from the Clarence T.C. Ching Athletics Complex in Honolulu is set for 11 p.m. ET. The game will be televised nationally on CBS Sports Network. The Cardinal are 3-point favorites in the latest Stanford vs. Hawaii odds, while the over/under for total points scored is 55. Before making any Hawaii vs. Stanford picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, the proprietary computer model has generated a stunning profit of almost $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Stanford vs. Hawaii and just locked in its picks and CFB picks and predictions. You can visit SportsLine now to see the model's picks. Here are the college football odds and betting lines for Hawaii vs. Stanford:

  • Hawaii vs. Stanford spread: Stanford -3
  • Hawaii vs. Stanford over/under: 55 points 
  • Hawaii vs. Stanford money line: Stanford -154, Hawaii +129
  • STAN: 0-9 in 2022 when allowing more than 14 points (3-0 when allowing 14 or fewer)
  • HAW: Won 3 consecutive home games vs Pac-12 opponents (Haven't lost at home vs Pac-12 school since 2014 vs Oregon State)
  • Hawaii vs. Stanford picks: See picks at SportsLine

Why Stanford can cover

Taylor starts with essentially a blank slate for the Cardinal, who return only three starters each on offense and defense. Taylor comes from Sacramento State, where he compiled a 30-8 record, including 23-1 in Big Sky Conference games. It was his first head coaching position after previously being the offensive coordinator under Kyle Whittingham for two seasons at Utah.

The Cardinal return running back E.J. Smith, son of the NFL Hall-of Famer Emmitt Smith, to lead their rushing attack. In two games last season before getting hurt, the younger Smith rushed for 208 yards on 30 carries and three touchdowns. Stanford is keeping its starting quarterback secret in advance of gametime, with Ari Patu, Ashton Daniels and Justin Lamson all in the conversation.

Why Hawaii can cover 

Hawaii trailed 35-14 at Vanderbilt last week before scoring two touchdowns and driving for the tying score before falling short. It was quite the turnaround from the 63-10 drubbing they suffered at the hands of the Commodores in Honolulu last season. Junior quarterback Brayden Schager threw for 351 yards and three touchdowns in the defeat, though his two interceptions were costly. Schager's main targets were wide receivers Pofele Ashlock (7-127-1) and Steven McBride (7-98-2), who should do damage this week against an inexperienced Stanford secondary.

One area Hawaii needs to improve is their rushing attack, which was non-existent against Vanderbilt. The Rainbow Warriors generated only 40 yards on 25 carries, though the SEC team didn't do much better, as Vandy rushed for 39 yards on 26 attempts against the Hawaii defense. Against a Stanford team with few returning starters, Hawaii has a solid chance to pull the minor upset in Week 1. See which team to pick here.

How to make Stanford vs. Hawaii picks

SportsLine's model is leaning Under on the point total. It has also generated an against-the-spread pick that hits in well over 50% of simulations. You can only get the model's picks and analysis at SportsLine. 

So who wins Stanford vs. Hawaii, and which side of the spread cashes in well over 50% of simulations? Visit SportsLine now to see which side of the Hawaii vs. Stanford spread to jump on, all from the advanced model that finished up nearly $2,500 on its FBS college football picks since its inception, and find out.