The Orioles designated Vespi for assignment on Sunday, Cordell Woodland of 105.7 The Fan Baltimore reports.
The left-hander was optioned to Triple-A Norfolk on Friday and has now lost his place on Baltimore's 40-man roster. Vespi has a 2.92 ERA, 1.05 WHIP and 9:3 K:BB over 12.1 major-league innings this year, though he's struggled to a 7.71 ERA at Triple-A.