Booker (ankle) has been ruled out for Sunday's game in San Francisco, Paul Gutierrez of the Raiders' official site reports.
Booker was limited in practice Wednesday, then sat out the sessions Thursday and Friday entirely. He's thus set to miss his first game of the campaign. Booker typically plays one-third to one-half of Las Vegas' defensive snaps, and Tonka Hemingway may be asked to log a bigger workload with Booker sidelined.