Offensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Quarterback | G. SmithGeno Smith | K. PickettKenny Pickett | |
| Running Back | A. JeantyAshton Jeanty | R. MostertRaheem Mostert | |
| Wide Receiver | T. TuckerTre Tucker | T. LockettTyler Lockett | |
| Tight End | B. BowersBrock Bowers | M. MayerMichael Mayer | |
| Left Tackle | S. ForsytheStone Forsythe | C. GrantCharles Grant | |
| Left Guard | D. ParhamDylan Parham | — | — |
| Center | W. PutnamWill Putnam | A. CappaAlex Cappa | — |
| Right Guard | J. MeredithJordan Meredith | C. RogersCaleb Rogers | |
| Right Tackle | D. GlazeDelmar Glaze | S. ForsytheStone Forsythe | — |
Defensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Left Defensive End | M. CrosbyMaxx Crosby | T. WilsonTyree Wilson | — |
| Right Defensive End | M. KoonceMalcolm Koonce | C. SnowdenCharles Snowden | |
| Left Defensive Tackle | J. LauluJonah Laulu | T. BookerThomas Booker | — |
| Right Defensive Tackle | A. ButlerAdam Butler | J. PeguesJJ Pegues | |
| Strongside Linebacker | D. WhiteDevin White | C. LindenbergCody Lindenberg | |
| Middle Linebacker | E. RobertsElandon Roberts | T. EichenbergTommy Eichenberg | — |
| Weakside Linebacker | J. AdamsJamal Adams | J. RhattiganJon Rhattigan | — |
| Right Cornerback | E. StokesEric Stokes | — | — |
| Left Cornerback | K. KellyKyu Blu Kelly | D. PorterDarien Porter | |
| Slot Cornerback | D. HolmesDarnay Holmes | J. AdamsJamal Adams | |
| Strong Safety | J. ChinnJeremy Chinn | L. JohnsonLonnie Johnson | — |
| Free Safety | I. Pola-MaoIsaiah Pola-Mao | T. McCollumTristin McCollum | — |
Special Teams Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Punter | A. ColeA.J. Cole | — | — |
| Kicker | D. CarlsonDaniel Carlson | — | — |
| Long Snapper | J. BobenmoyerJacob Bobenmoyer | — | — |
| Holder | A. ColeA.J. Cole | — | — |
| Punt Returner | T. TuckerTre Tucker | A. JeantyAshton Jeanty | — |
| Kick Returner | R. MostertRaheem Mostert | T. TuckerTre Tucker |