Ohio State vs. Maryland prediction, odds: 2022 Week 12 college football picks, best bets by proven simulation
SportsLine's model just revealed its CFB picks, predictions and best bets for Maryland Terrapins vs. Ohio State Buckeyes

The Maryland Terrapins try to finally get in the win column when they host the No. 2 Ohio State Buckeyes in a Big Ten clash on Saturday. Maryland (6-4, 3-4 Big Ten) has lost all seven of its meetings with Ohio State, with six of the defeats coming by at least 21 points. The Terrapins, who are coming off a 30-0 loss at then-No. 14 Penn State, were demolished 66-17 in last year's matchup against the Buckeyes. Ohio State (10-0, 7-0) has recorded all 10 of its wins in 2022 by double digits, including last week's 56-14 rout of Indiana.
Kickoff at SECU Stadium in College Park, Md.is set for 3:30 p.m. ET. The Buckeyes are 27-point favorites in the latest Ohio State vs. Maryland odds from Caesars Sportsbook, while the over/under for total points scored is 62.5. Before making any Maryland vs. Ohio State picks, you need to see the college football predictions and betting advice from SportsLine's advanced computer model.
The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.
Now, the model has set its sights on Ohio State vs. Maryland and locked in its picks and CFB predictions. You can head to SportsLine now to see the model's picks. Here are several college football odds and betting lines for Maryland vs. Ohio State:
- Ohio State vs. Maryland spread: Buckeyes -27
- Ohio State vs. Maryland over/under: 62.5 points
- Ohio State vs. Maryland money line: Buckeyes -4500, Terrapins +1550
- OSU: The Buckeyes are 1-4 against the spread in their last five road games
- MD: The Terrapins are 2-8 ATS in their last 10 contests following a straight-up loss
- Ohio State vs. Maryland picks: See picks at SportsLine
Why Ohio State can cover
The Buckeyes have yet to lose to Maryland, going 7-0 overall and 3-0 on the road. Six of the victories have been by at least 21 points, including last year's 66-17 rout in which C.J. Stroud completed 24-of-33 pass attempts for 406 yards and five touchdowns. The junior quarterback had made at least five TD tosses this season, most recently doing so last week versus the Hoosiers, and is tied for first in the nation with 34 against only four interceptions.
Ohio State hopes to have its top two running backs available against the Terrapins. Junior Miyan Williams, who leads the team with 783 rushing yards and 13 touchdown runs, exited last week's game in the second quarter with an ankle injury after 147 yards and a score. Meanwhile, sophomore TreVeyon Henderson, who ran for 102 yards and two TDs while also hauling in a scoring pass in last year's win against Maryland, has missed the last two contests with a foot ailment.
Why Maryland can cover
Ohio State is the second-best team in the nation at scoring touchdowns on red-zone drives, doing so 81.6% of the time. The Terrapins are no slouch in that category, however, as they've gotten into the end zone 26 times on their 33 trips inside the 20-yard line (78.8%) to rank fourth in the country. Roman Hemby leads the team with eight overall TDs, including seven on the ground.
The redshirt freshman is third in the Big Ten with an average of 6.1 yards per carry, racking up 815 on 134 attempts this season. Hemby also had been a factor in Maryland's aerial attack as he has made 27 catches for 239 yards and a touchdown. He tops all FBS freshmen with 1,054 scrimmage yards and has reached triple digits in rushing yards four times, with his highest output being a 179-yard performance on Oct. 22 against Northwestern.
How to make Maryland vs. Ohio State picks
SportsLine's model is leaning Under on the total, projecting a combined 62 points. The model also says one side of the spread hits in well over 50% of simulations. You can only see the model's CFB picks at SportsLine.
So who wins Ohio State vs. Maryland? And which side of the spread hits in well over 50% of simulations? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has crushed its college football picks, and find out.















